265983-08-2Relevant academic research and scientific papers
PYRIDINE DERIVATIVES AS DIPEPTEDYL PEPTIDASE INHIBITORS
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Page/Page column 45, (2008/06/13)
The present invention is directed to compounds of formula (I) or a pharmaceutically acceptable salt thereof; wherein A is (1); X is selected from CH, CF and N; R5 is selected from H, C1-C6 alkyl, C1-C6 fluoroalk
Highly enantioselective phase-transfer-catalyzed alkylation of protected α-amino acid amides toward practical asymmetric synthesis of vicinal diamines, α-amino ketones, and α-amino alcohols
Ooi, Takashi,Takeuchi, Mifune,Kato, Daisuke,Uematsu, Yukitaka,Tayama, Eiji,Sakai, Daiki,Maruoka, Keiji
, p. 5073 - 5083 (2007/10/03)
Highly enantioselective alkylation of protected glycine diphenylmethyl (Dpm) amide 1 and Weinreb amide 10 has been realized under phase-transfer conditions by the successful utilization of designer chiral quaternary ammonium salts of type 4 as catalyst. P
