265987-99-3Relevant academic research and scientific papers
ALKYLBORONIC ACIDS AS ARGINASE INHIBITORS
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Page/Page column 1010946-0948, (2020/08/22)
Provided are alkylboronic acids as arginase inhibitors represented by formula (I), or a pharmaceutically acceptable salt, stereoisomer, tautomer, or prodrug thereof and a pharmaceutical composition comprising said compounds.
HETEROCYCLIC COMPOUNDS AS ARGINASE INHIBITORS
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Page/Page column 66, (2019/07/13)
The present invention relates to heterocyclic compounds as arginase inhibitors, in particular to a compound represented by Formula (I), or a pharmaceutically acceptable salt, stereoisomer or tautomer, or prodrug thereof and a pharmaceutical composition comprising said compound.
Cyclopropane PNA: Observable triplex melting in a PNA constrained with a 3-membered ring
Pokorski, Jonathan K.,Myers, Michael C.,Appella, Daniel H.
, p. 915 - 917 (2007/10/03)
The first peptide nucleic acid (PNA) with a cyclopropane in the backbone has been synthesized, and the effects of the ring on DNA/RNA binding properties of the PNA have been examined. Well-defined triplex to duplex melting transitions of PNA2 DNA complexes is clearly observed by variable temperature UV absorbance with the cyclopropane-constrained PNA.
Benzamides derived from 1,2-diaminocyclopropane as novel ligands for human D2 and D3 dopamine receptors
Yang, Donglai,Kefi, Slaheddine,Audinot, Valerie,Millan, Mark-J.,Langlois, Michel
, p. 321 - 327 (2007/10/03)
Benzamides (3a-f) derived from 4-amino-5-chloro-2-methoxybenzoic acid and either cis or trans 1,2-diaminocyclopropane were synthesised and were evaluated in binding assays employing, bovine striatal D2 receptors, recombinant human hD2/sub
