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2,2-dimethyl-6-nitro-2H-1,4-benzothiazin-3(4H)-one is a chemical compound belonging to the benzothiazinone family, characterized by the molecular formula C9H9N3O3S. It is recognized for its potential as an antimycobacterial agent, particularly against Mycobacterium tuberculosis, the causative agent of tuberculosis. 2,2-dimethyl-6-nitro-2H-1,4-benzothiazin-3(4H)-one has demonstrated promising inhibitory activity in preclinical studies, making it a valuable candidate for further research and development in the pharmaceutical industry.

265994-70-5

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265994-70-5 Usage

Uses

Used in Pharmaceutical Industry:
2,2-dimethyl-6-nitro-2H-1,4-benzothiazin-3(4H)-one is used as an antimycobacterial agent for the development of new drugs to treat tuberculosis. Its unique ability to target the TB-causing bacteria makes it a promising candidate for the creation of more effective treatments against this disease.
Used in Drug Development:
2,2-dimethyl-6-nitro-2H-1,4-benzothiazin-3(4H)-one is utilized in the research and development of novel therapeutic agents. Its potential to inhibit the growth of Mycobacterium tuberculosis positions it as a key component in the advancement of new drug formulations aimed at combating tuberculosis, a disease that continues to pose significant health challenges worldwide.

Check Digit Verification of cas no

The CAS Registry Mumber 265994-70-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,5,9,9 and 4 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 265994-70:
(8*2)+(7*6)+(6*5)+(5*9)+(4*9)+(3*4)+(2*7)+(1*0)=195
195 % 10 = 5
So 265994-70-5 is a valid CAS Registry Number.

265994-70-5 Well-known Company Product Price

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  • Alfa Aesar

  • (H61008)  2,2-Dimethyl-6-nitro-2H-1,4-benzothiazin-3(4H)-one, 97%   

  • 265994-70-5

  • 250mg

  • 318.0CNY

  • Detail

  • Alfa Aesar

  • (H61008)  2,2-Dimethyl-6-nitro-2H-1,4-benzothiazin-3(4H)-one, 97%   

  • 265994-70-5

  • 1g

  • 1016.0CNY

  • Detail

265994-70-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 3,4-dihydro-2,2-dimethyl-6-nitro-2H-1,4-benzothiazin-3-one

1.2 Other means of identification

Product number -
Other names 2,2-dimethyl-6-nitro-2H-1,4-benzothiazin-3(4H)-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:265994-70-5 SDS

265994-70-5Relevant academic research and scientific papers

Highly potent 1,4-benzothiazine derivatives as KATP-channel openers

Cecchetti, Violetta,Calderone, Vincenzo,Tabarrini, Oriana,Sabatini, Stefano,Filipponi, Enrica,Testai, Lara,Spogli, Roberto,Martinotti, Enrica,Fravolini, Arnaldo

, p. 3670 - 3679 (2003)

A series of 1,4-benzothiazines, suitably functionalized at the N-4 and C-6 positions, arising from the replacement of a benzopyran-based structure of cromakalim with a 1,4-benzothiazine nucleus, has been synthesized as potassium channel openers (KCOs). Mo

Novel potassium channel openers. Part 4: Transformation of the 1,4- benzoxazine skeleton into 1,4-benzothiazine, 1,2,3,4-tetrahydroquinoline, 1,2,3,4-tetrahydroquinoxaline, indoline, and 1,5-benzoxazepine

Matsumoto, Yuzo,Tsuzuki, Ryuji,Matsuhisa, Akira,Yoden, Toru,Yamagiwa, Yoko,Yanagisawa, Isao,Shibanuma, Tadao,Nohira, Hiroyuki

, p. 393 - 404 (2007/10/03)

As part of a search for a new potassium channel opener, the 1,4- benzoxazine skeleton derived from the benzopyran skeleton of cromakalim, was transformed into other fused rings such as 1,4-benzothiazine, 1,2,3,4- tetrahydroquinoline, 1,2,3,4-tetrahydroqui

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