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4-[2-(1H-indol-3-yl)ethenyl]-1-methylpyridinium is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

26608-75-3

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26608-75-3 Usage

Main Properties

1. Chemical Name: 4-[2-(1H-indol-3-yl)ethenyl]-1-methylpyridinium
2. Commonly Known As: MPP+
3. Type: Synthetic organic chemical compound
4. Usage: Induces parkinsonism in laboratory animals

Specific Content

1. Toxin that targets and damages dopaminergic neurons
2. Leads to symptoms similar to Parkinson's disease
3. Metabolite of the herbicide paraquat
4. Causes cellular damage through production of reactive oxygen species and mitochondrial dysfunction
5. Studied as a model for neurodegenerative diseases
6. Investigates mechanisms of neuronal death
7. Used to study transport of neurotransmitters in the central nervous system.

Check Digit Verification of cas no

The CAS Registry Mumber 26608-75-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,6,6,0 and 8 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 26608-75:
(7*2)+(6*6)+(5*6)+(4*0)+(3*8)+(2*7)+(1*5)=123
123 % 10 = 3
So 26608-75-3 is a valid CAS Registry Number.

26608-75-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-[(E)-2-(1-methylpyridin-1-ium-4-yl)ethenyl]-1H-indole,iodide

1.2 Other means of identification

Product number -
Other names BB_NC-0786

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:26608-75-3 SDS

26608-75-3Downstream Products

26608-75-3Relevant academic research and scientific papers

Pyridinium and indole orientation determines the mitochondrial uncoupling and anti-cancer efficiency of F16

Xu, Juan,He, Huan,Zhou, Lian-Jiao,Liu, Yu-Zhu,Li, Dong-Wei,Jiang, Feng-Lei,Liu, Yi

, p. 305 - 313 (2018)

F16 is a mitochondria-targeted, broad-spectrum anticancer agent in the pre-clinic cancer therapy. Here we developed two fluorescent isomers of F16 (o-F16 and m-F16) with entirely different photophysical properties, uncoupling activity, and cytotoxicity by

RNA-selective probes for live cell imaging of nuclear structure and function

-

Page/Page column 40, (2010/09/09)

The present invention is directed to fluorescent compounds and methods of making said compounds that selectively bind to cellular RNA. The fluorescent compounds of the present invention are useful for live cell imaging applications.

Combinatorial approach to organelle-targeted fluorescent library based on the styryl scaffold

Rosania, Gustavo R.,Lee, Jae Wook,Ding, Liang,Yoon, Hai-Shin,Chang, Young-Tae

, p. 1130 - 1131 (2007/10/03)

The first fluorescent styryl dye library with a broad color range was synthesized by combinatorial condensation of various aldehydes and methyl pyridinium compounds, and their applications as organelle specific staining probes were demonstrated. Copyright

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