26619-80-7

Basic information

• Product Name: (2R)-1-[(2R)-piperidin-2-yl]propan-2-ol
• CAS NO: 26619-80-7
• Molecular Formula: C₈H₁₇NO
• Molecular Weight: 143.2267
• Mol File: 26619-80-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 244.1°C at 760 mmHg
• Flash Point: 97.9°C
• Density: 0.927g/cm³
• Vapor Pressure: 0.0052mmHg at 25°C
• Refractive Index: 1.454
• CAS DataBase Reference: (2R)-1-[(2R)-piperidin-2-yl]propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-1-[(2R)-piperidin-2-yl]propan-2-ol(26619-80-7)
• EPA Substance Registry System: (2R)-1-[(2R)-piperidin-2-yl]propan-2-ol(26619-80-7)

Safety Data

• Hazardous Substances Data: 26619-80-7(Hazardous Substances Data)

Usage

General Description

"(2R)-1-[(2R)-piperidin-2-yl]propan-2-ol" is a chemical compound with the molecular formula C9H19NO. It is an alcohol derivative with a piperidine ring and an isopropyl group attached to it. The compound is a chiral molecule, meaning it has two enantiomers that are mirror images of each other. (2R)-1-[(2R)-piperidin-2-yl]propan-2-ol may have potential applications in pharmaceuticals, as piperidine derivatives are commonly found in many drugs and biologically active compounds. The specific properties and potential uses of "(2R)-1-[(2R)-piperidin-2-yl]propan-2-ol" would need to be further studied and determined.

Upstream product

• 4396-01-4 isopelletierine 
• 14199-09-8 benzyl 2-(2-hydroxypropyl)piperidine-1-carboxylate 
• 1191-30-6 5-bromopentanal 
• 26619-95-4 1-(1-benzyl-piperidin-2-yl)-propan-2-ol 
• 70546-91-7 Methanesulfonic acid (2S,3aS)-1-(hexahydro-isoxazolo[2,3-a]pyridin-2-yl)methyl ester 
• 241132-72-9 2-hydroxymethylhexahydro-2H-isoxazolo<2,3-a>pyridine 
• 34418-91-2 2,3,4,5-tetrahydropyridine N-oxide 
• 4801-58-5 N-hydroxypiperidine 
• 70546-87-1 (2S,3aR)-2-Methyl-hexahydro-isoxazolo[2,3-a]pyridine 
• 137128-40-6 (3R,4aR)-3-Methyl-4,4a,5,6-tetrahydro-3H-pyrido[1,2-c][1,3]oxazin-1-one 
• 70546-91-7 Methanesulfonic acid (2S,3aR)-1-(hexahydro-isoxazolo[2,3-a]pyridin-2-yl)methyl ester 
• 6302-02-9 2-acetonylpyridine 
• 70546-87-1 2-methyl-hexahydro-isoxazolo[2,3-a]pyridine 
• 137105-67-0 (3RS,5RS)-3-methylhexahydro-3H-pyrido[1,2-c][1,3]oxazin-1-one 

Relevant articles and documents

Proline catalyzed, one-pot three component Mannich reaction and sequential cyclization toward the synthesis of 2-substituted piperidine and pyrrolidine alkaloids

Abstract A very effective one-pot three component reaction of 4-bromobutanal or 5-bromopentanal, acetone, and p-anisidine catalyzed by proline is reported. A three component Mannich reaction followed by cyclization leading to the synthesis of 2-substituted pyrrolidine and piperidine derivatives through simultaneous formation of two C-N and one C-C bond is reported. The usefulness of the reaction is demonstrated by the synthesis of (±)coniine, (±)pelletrine, (±)sedridine, and (±)allosedridine.

DIASTEREOSELECTIVE INTRAMOLECULAR DIELS-ALDER RECTION OF N-ALKOXYCARBONYL-1-AZA-1,3-BUTADIENES AND A TOTAL SYNTHESIS OF THE PIPERIDINE ALKALOID, (+/-)-SEDRIDINE

Total synthesis of (+/-)-sedridine, the piperidine alkaloid, was accomplished on the basis of diastereoselective intramolecular Diels-Alder reaction of the ψ',ω'-unsaturated N-alkoxycarbonyl-1-aza-1,3-butadiene generated in situ from N-trimethylsilyl-1-az

The stereochemistry of nitrone cycloadditions. dl-allosedamine and dl-sedridine

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