26625-33-2Relevant articles and documents
Synthesis and Stereoselective Reduction of (+/-)-, (+)- and (-)-6-Substituted-6-azabicyclooctan-3-one
Pitner, J. Bruce,Abraham, Philip,Joo, Young J.,Triggle, David J.,Carroll, F. Ivy
, p. 1375 - 1381 (2007/10/02)
Starting with 6-oxabicyclooct-3-en-7-one 6, a three step, general synthetic route to both racemic and optically active 6-substituted 6-azabicyclooctan-3-ones has been developed.Opening of the lactone ring of 6 with amines gave amides which w