266338-24-3

Usage

Uses

Used in Fragrance Industry:
Cyclocitral is used as a fragrance ingredient for its citrus-like scent, adding a pleasant aroma to various products. Its natural occurrence and appealing smell make it a popular choice in the creation of perfumes, colognes, and other scented products.
Used in Flavoring Industry:
In the food and beverage sector, cyclocitral is used as a flavoring agent to impart a citrus flavor to products, enhancing their taste and consumer appeal.
Used in Pharmaceutical Industry:
Cyclocitral is studied for its potential anti-inflammatory properties, making it a candidate for development in pharmaceutical applications where such properties are beneficial for treating inflammation-related conditions.
Used in Cosmetic Industry:
Due to its antioxidant properties, cyclocitral is utilized in the cosmetic industry to protect the skin from oxidative stress, potentially contributing to anti-aging and skin health products.
Used in Research:
Cyclocitral's potential anti-inflammatory and antioxidant properties also make it a subject of interest in scientific research, where it could be further explored for its therapeutic effects and mechanisms of action.

Upstream product

• 90-15-3 α-naphthol 
• 1165952-91-9 cyclohexa-1,3-diene 

Relevant academic research and scientific papers

Rearrangements of Cycloalkenyl Aryl Ethers

Rearrangement reactions of cycloalkenyl phenol and naphthyl ethers and the acid-catalyzed cyclization of the resulting product were investigated. Claisen rearrangement afforded 2-substituted phenol and naphthol derivatives. Combined Claisen and Cope rearrangement resulted in the formation of 4-substituted phenol and naphthol derivatives. In the case of cycloocthylphenyl ether the consecutive Claisen and Cope rearrangements were followed by an alkyl migration. The mechanism of this novel rearrangement reaction is also discussed.

Synthesis and inhibitory evaluation of cyclohexen-2-yl- and cyclohexyl-substituted phenols and quinones to endothelial cell and cancer cells

Alkylation of phenols with 1,3-cyclohexadiene (1) has been conducted and a series of cyclohexen-2-yl- and cyclohexyl-substituted phenols and quinones were screened against the proliferation of HUVEC and cancer cells. Phenol type as well as the size and occupied position of the substitute are important for the alkylating reaction and the inhibitory activity and selectivity of a compound. 2,5-Di(cyclohexen-2-yl)benzene-1,4-diol (25) bearing two cyclohexen-2-yl groups and 2-tert-butyl-5-(cyclohexen-2-yl)benzene-1,4-diol (30) bearing cyclohexen-2-yl and tert-butyl groups exhibited good selectivity against HUVEC proliferation (IC50s of 2.0 and 1.4?μM, respectively) with relatively low toxicity to ccc-HPF-1.