266352-06-1

Upstream product

• 266352-04-9 5-(4-ethoxyphenyl)-4-methylpent-2E,4E-dienal 
• 65201-77-6 tetrabutylammonium periodite 

Downstream Products

• 266352-09-4 3,6-dihydro-6-(4-ethoxyphenyl)-3-hydroxymethyl-5-methyl-2H-1,2-oxazine hydrochloride 

Relevant academic research and scientific papers

Use of n-substituted (3,6-dihydro)-2h-1,2-oxazine derivatives as selective mglur1 antagonists

STR1Use of a compound of formula (I) in which, R 1, R 2 and R 3 are independently hydrogen, (C 1 -C 6)alkyl, (C 2 -C 6)alkenyl, C 3 -C 10)cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted aryl(C 1 -C 6)alkyl, unsubstituted or substituted aryl(C 2 -C 6)alkenyl, halo, carboxy, (C 1 -C 6)alkoxycarbonyl or --(CH 2) m --OH wherein m is 1, 2 or 3; - - - indicates a single or a double bond; X and each independently hydrogen, or X and Y together represent a bridge of the formula --CH 2) m --, where n is 1 or 2; A 1 and A 2 are each independently an unsubstituted or substituted aryl; Z is --CO--, --SO 2 -- or --CH 2 ; provided that, when Z is --CO--, A 1 is not 3,4,5-trimethoxyphenyl; or a pharmaceutically-acceptable salt or ester thereof, for the manufacture of a medicament for the treatment of a condition indicating the administration of a selective mGluR1 antagonist.