266679-85-0

Basic information

• Product Name: benzhydryl 4-acetylbenzoate
• Synonyms: benzhydryl 4-acetylbenzoate
• CAS NO: 266679-85-0
• Molecular Weight: 330.383
• Mol File: 266679-85-0.mol

Chemical Properties

• CAS DataBase Reference: benzhydryl 4-acetylbenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: benzhydryl 4-acetylbenzoate(266679-85-0)
• EPA Substance Registry System: benzhydryl 4-acetylbenzoate(266679-85-0)

Safety Data

• Hazardous Substances Data: 266679-85-0(Hazardous Substances Data)

Upstream product

• 91-01-0 1,1-Diphenylmethanol 
• 586-89-0 4-acetyl-benzoic acid 
• 908093-98-1 diazodiphenylmethane 

Downstream Products

• 266679-75-8 4-{1-[(E)-1-Benzylcarbamoyl-3,3-diethyl-4-oxo-azetidin-2-yloxyimino]-ethyl}-benzoic acid benzhydryl ester 
• 266679-72-5 4-{1-[(E)-3,3-Diethyl-4-oxo-azetidin-2-yloxyimino]-ethyl}-benzoic acid benzhydryl ester 
• 266679-58-7 4-{1-[(E)-Hydroxyimino]-ethyl}-benzoic acid benzhydryl ester 

Relevant articles and documents

Facile synthesis of diphenylmethyl esters from 2-diphenylmethoxypyridine using catalytic boron trifluoride·diethyl etherate

A practical method for the direct preparation of diphenylmethyl (DPM) esters from 2-diphenylmethoxypyridine is described. The reaction was readily performed in the presence of a catalytic amount of boron trifluoride-diethyl etherate at room temperature. Using this reaction protocol, various carboxylic acids were converted to DPM esters with high yields. This method is highly effective for the protection of carboxylic acids and the synthesis of DPM esters, and offers a promising approach for facile esterification of a variety of carboxylic acids.

Synthesis, inhibitory activity towards human leukocyte elastase and molecular modelling studies of 1-carbamoyl-4-methyleneaminoxyazetidinones

Some monocyclic β-lactam derivatives of type 3 (MAOAs) in which the leaving group (LG) on the C(4) is a methyleneaminoxy moiety, were synthesised and tested in vitro and in vivo for their inhibitory activity towards human leukocyte elastase (HLE). Some compounds showed an appreciable in vitro inhibitory activity against this enzyme. Effects on the anti-HLE activity due to the nature of the substituents R and R1 present on their LG were observed and rationalised by means of molecular modelling techniques. The results of in vivo pharmacological tests indicated that MAOAs, while showing an inhibitory activity on the haemorrhage induced by HLE, did not exhibit any effects due to the R and R1 substituents. (C) 2000 Editions scientifiques et medicales Elsevier SAS.