266683-40-3

Basic information

• Product Name: [Ni(C₆H₅)CH₂NH((CH₂)3CH)CON(C₆H₄)C(C₆H₅)NCH(CH₂CH₂CCH)COO]
• CAS NO: 266683-40-3
• Molecular Weight: 551.287
• Mol File: 266683-40-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [Ni(C₆H₅)CH₂NH((CH₂)3CH)CON(C₆H₄)C(C₆H₅)NCH(CH₂CH₂CCH)COO](CAS DataBase Reference)
• NIST Chemistry Reference: [Ni(C₆H₅)CH₂NH((CH₂)3CH)CON(C₆H₄)C(C₆H₅)NCH(CH₂CH₂CCH)COO](266683-40-3)
• EPA Substance Registry System: [Ni(C₆H₅)CH₂NH((CH₂)3CH)CON(C₆H₄)C(C₆H₅)NCH(CH₂CH₂CCH)COO](266683-40-3)

Safety Data

• Hazardous Substances Data: 266683-40-3(Hazardous Substances Data)

Upstream product

• 38771-21-0 4-bromobut-1-yne 
• 172924-51-5 [Ni(C₆H₅)CH₂NH((CH₂)3CH)CON(C₆H₄)C(C₆H₅)NCH₂COO] 

Relevant articles and documents

Synthesis and evaluation of ω-borono-α-amino acids as active-site probes of arginase and nitric oxide synthases

Enantiomerically pure ω-borono-α-amino acids of various chain lengths have been synthesized according to a general methodology involving condensation of alkenyl and alkynyl bromides with NiII complex of the Schiff base derived from glycine and (S)-2-[N'-(N-benzylprolyl)amino]benzophenone, hydroboration of the intermediate ω-unsaturated α-amino acids with diisopinocampheylborane, and oxidation with acetaldehyde. Some of these compounds act as potent inhibitors of rat liver and murine macrophage arginases, demonstrating that distance between the B(OH)2 and α-amino acid groups is a key determinant for their interaction with arginase. In contrast, they are without effect on neuronal and inducible NO synthases.