267014-74-4 Usage
Uses
Used in Medicinal Chemistry:
(2S,4R)-4-Methoxymethoxy-pyrrolidine-1,2-dicarboxylic acid dibenzyl ester is used as a building block in medicinal chemistry for the development of new pharmaceuticals. Its specific stereochemistry and functional groups may contribute to its interaction with biological targets, making it a promising candidate for drug discovery and design.
Used in Organic Synthesis:
In the field of organic synthesis, (2S,4R)-4-Methoxymethoxy-pyrrolidine-1,2-dicarboxylic acid dibenzyl ester serves as an intermediate or a precursor for the synthesis of other complex organic molecules. Its unique structure and reactivity can be leveraged to create a variety of compounds with diverse applications.
Further research is necessary to fully understand the properties and potential uses of this chemical compound, as its complex structure and stereochemistry may offer novel opportunities in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 267014-74-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,7,0,1 and 4 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 267014-74:
(8*2)+(7*6)+(6*7)+(5*0)+(4*1)+(3*4)+(2*7)+(1*4)=134
134 % 10 = 4
So 267014-74-4 is a valid CAS Registry Number.
267014-74-4Relevant academic research and scientific papers
Catalysis with phosphine-containing amino acids in various "turn" motifs
Agarkov, Anton,Greenfield, Scott J.,Ohishi, Takahiro,Collibee, Scott E.,Gilbertson, Scott R.
, p. 8077 - 8085 (2007/10/03)
We have been actively involved in the development of parallel approaches for the discovery of phosphine ligands. Our approach has been based on the incorporation of phosphine-containing amino acids into peptide sequences that are designed to have stable secondary structures. We have examined helical and turn secondary structures and have reported that alkylation of cyclopentenyl acetate with dimethylmalonate can be catalyzed in high enantiomeric excess (ee) with a β-turn-based ligand. The importance of the peptide secondary structure was demonstrated through the synthesis of a series of peptide ligands where the nature of the turn-forming residues was probed. Additionally, other turn-forming units and a variety of different phosphine-containing amino acids have been examined for their ability to control the selectivity of the allylation reaction. This paper reports the results obtained through the examination of different turn motifs as well as different phosphine substitutions on the "best" turn sequence, Pps-Pro-D-Xxx-Pps.
