26733-62-0

Upstream product

• 60437-30-1 4-hydroxy-4-(methoxycarbonyl)-1-(phenylmethyl)piperidine 
• 57-13-6 urea 
• 1189-71-5 isocyanate de chlorosulfonyle 
• 6094-60-6 1-benzyl-4-hydroxypiperidine-4-carbonitrile 

Downstream Products

• 26728-07-4 3,8-dibenzyl-1-oxa-3,8-diaza-spiro[4.5]decane-2,4-dione 
• 26786-44-7 8-benzyl-3-methyl-1-oxa-3,8-diaza-spiro[4.5]decane-2,4-dione 
• 343327-63-9 3-benzyl-1-oxa-3,8-diaza-spiro[4.5]decane-2,4-dione 
• 49614-61-1 3-benzyl-8-[3-(2-chloro-phenothiazin-10-yl)-propyl]-1-oxa-3,8-diaza-spiro[4.5]decane-2,4-dione 
• 26786-40-3 8-benzyl-3-propyl-1-oxa-3,8-diaza-spiro[4.5]decane-2,4-dione 
• 27894-41-3 8-benzyl-3-ethyl-1-oxa-3,8-diaza-spiro[4.5]decane-2,4-dione 

Relevant academic research and scientific papers

1,3,8-TRIAZA- AND 3,8-DIAZA-1-OXASPIRO[4,5] DECANE DERIVATIVES

Heterocyclic compounds of Formula I: STR1 in which n is 2, 3, 4, 5 or 6; t is 1, 2, 3 or 4; u is 0 or 1 (provided that t is not 1 when u is 0); X is O or N(R 4); Y and Z are independently C(O), C(S) or CH 2 (provided that Y and Z are not both CH 2); R 1, R. sup.2, R 3, and R 4 are as defined in the specification; and their pharmaceutically acceptable salts and N-oxides, formulations containing them, their uses as therapeutic agents, and their synthesis.

Study of the reaction between cyanohydrins and chlorosulfonyl isocyanate. A new, efficient method for the one-pot synthesis of 2,4-oxazolidinediones

The reaction between cyanohydrins and chlorosulfonyl isocyanate, followed by acid hydrolysis, provides and efficient route for the one-pot preparation of 5,5-disubstituted 2,4-oxazolidinediones.