267401-99-0

Upstream product

• 126-81-8 dimedone 
• 13148-87-3 3-hydroxy-5,5-dimethyl-2-(2-oxopropyl)-2-cyclohex-1-one 
• 163083-12-3 1-(4-nitrophenyl)-2,6,6-trimethyl-4,5,6,7-tetrahydroindol-4-one 

Downstream Products

• 267402-07-3 6H-1-(4-nitrophenyl)-2,7,7-trimethyl-4,5,7,8-tetrahydropyrrolo[3,2-c]azepin-4-thione 
• 267402-13-1 1-(4-nitrophenyl)-2,7,7-trimethyl-4-methylsulfanyl-4,5,7,8-tetrahydropyrrolo[3,2-c]azepine 
• 267402-00-6 6H-1-(4-nitrophenyl)-2,7,7-trimethyl-4,5,7,8-tetrahydropyrrolo[3,2-c]azepin-4-one 

Relevant academic research and scientific papers

Tetrahydropyrrolo[3,2-c]azepin-4-ones as a new class of cytotoxic compounds

Pyrroloazepinones 8a-j and 9a-j were designed by structural modification of lead compound 3. These compounds were tested on five tumor cell lines to determine the role of the azeto ring and the 2-methyl substituent in the cytotoxicity of compound 3. Our r