267425-72-9Relevant academic research and scientific papers
Synthesis of (-)-dysiherbaine.
Snider,Hawryluk
, p. 635 - 638 (2000)
[reaction: see text] The first synthesis of (-)-dysiherbaine has been accomplished using intramolecular SN2 substitutions of a carbamate anion on an epoxide and an alkoxide on a secondary mesylate to efficiently construct the bicyclic skeleton stereospecifically from xylose. A general sequence has been developed to introduce an allyl group and convert it to the alanine side chain that should be useful for the construction of dysiherbaine analogues.
