26751-24-6

Basic information

• Product Name: 4,5,6,7-Tetrahydro-1H-benzoimidazole-5-carboxylic acid
• Synonyms: 4,5,6,7-TETRAHYDRO-1H-BENZOIMIDAZOLE-5-CARBOXYLIC ACID;4,5,6,7-Tetrahydro-1H-benzoimidazole-5-carboxylic;4,5,6,7-Tetrahydro-1H-benzimidazole-5-carboxylic acid;4,5,6,7-tetrahydro-1H-1,3-benzodiazole-5-carboxylic acid;4,5,6,7-Tetrahydro-1h-benzoiMidazole-5-carboxylic acid, HCl;4,5,6,7-Tetrahydro-1H-benziMidazole-5-carboxylic;4,5,6,7-Tetrahydro-1H-benzo[d]iMidazole-5-carboxylic acid;1H-Benzimidazole-6-carboxylic acid, 4,5,6,7-tetrahydro-
• CAS NO: 26751-24-6
• Molecular Formula: C₈H₁₀N₂O₂
• Molecular Weight: 166.18
• EINECS: 1533716-785-6
• Product Categories: pharmacetical;Heterocycles
• Mol File: 26751-24-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 498.252 °C at 760 mmHg
• Flash Point: 255.134 °C
• Appearance: /
• Density: 1.384 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.611
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 3.94±0.20(Predicted)
• CAS DataBase Reference: 4,5,6,7-Tetrahydro-1H-benzoimidazole-5-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5,6,7-Tetrahydro-1H-benzoimidazole-5-carboxylic acid(26751-24-6)
• EPA Substance Registry System: 4,5,6,7-Tetrahydro-1H-benzoimidazole-5-carboxylic acid(26751-24-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 26751-24-6(Hazardous Substances Data)

Usage

Uses

4,5,6,7-Tetrahydro-1H-benzimidazole-5-carboxylic Acid is a conformationally restricted inhibitor of active thrombin activatable fibrinolysis inhibitor (TAFI) . Activated TAFI protects fibrin clots against lysis.

InChI:InChI=1/C8H10N2O2/c11-8(12)5-1-2-6-7(3-5)10-4-9-6/h4-5H,1-3H2,(H,9,10)(H,11,12)

Downstream Products

• 167545-77-9 5-[{3-(3-hydroxyphenyl)indolin-1-ylcarbonyl}]-4,5,6,7-tetrahydrobenzimidazole 
• 361395-11-1 4,5,6,7-Tetrahydro-1 H-benzimidazole-5-carboxylic acid (5-phenoxypentyl)-amide, Hydrochloride 
• 361395-04-2 4,5,6,7-Tetrahydro-1H-benzimidazole-5-carboxylic acid (5-phenylpentyl)amide, Hydrochloride 
• 361395-23-5 4,5,6,7-Tetrahydro-1H-benzimidazole-5-carboxylic acid (4-phenoxybutyl]-methylamide, Hydrochloride 
• 361395-21-3 4,5,6,7-Tetrahydro-1H-benzimidazole-5-carboxylic acid [3-(3-chlorophenoxy)-propyl]methylamide, Hydrochloride 
• 361395-18-8 4,5,6,7-Tetrahydro-1H-benzimidazole-5-carboxylic acid [3-(4-chlorophenyl)-propyl]methylamide, hydrochloride 
• 361395-09-7 4,5,6,7-Tetrahydro-1H-benzimidazole-5-carboxylic acid [4-(3-methylphenoxy)-butyl]amide, hydrochloride 
• 361395-08-6 4,5,6,7-Tetrahydro-1 H-benzimidazole-5-carboxylic acid [4-(4-methylphenoxy)-butyl]amide, Hydrochloride 
• 361395-07-5 4,5,6,7-Tetrahydro-1 H-benzimidazole-5-carboxylic acid [3-(3-chlorophenoxy)-propyl]amide, hydrochloride 
• 361394-39-0 4,5,6,7-tetrahydro-1H-benzimidazole-5-carboxylic acid 2-fluoro-6-(4-methoxy-phenoxy)-benzylamide, hydrochloride 
• 361395-03-1 4,5,6,7-Tetrahydro-1H-benzimidazole-5-carboxylic acid (3-phenylallyl)amide, Hydrochloride 
• 361395-19-9 4,5,6,7-Tetrahydro-1H-benzimidazole-5-carboxylic acid methyl(5-phenylpentyl)-amide, Hydrochloride 
• 361395-05-3 4,5,6,7-Tetrahydro-1H-benzimidazole-5-carboxylic acid (4-phenoxybutyl]amide, Hydrochloride 
• 361393-82-0 4,5,6,7-tetrahydro-1 H-benzimidazole-5-carboxylic acid N-(2-chloro-6-phenoxy-benzyl)amide