26758-53-2

Usage

Chemical structure

1-azabicyclo[2.2.2]oct-3-yl cyclopentyl(hydroxy)phenylacetate is a complex chemical compound with a bicyclic amine structure and a hydroxyphenylacetate group.

Category

It falls into the category of pharmacological compounds.

Potential applications

The chemical has potential applications in the field of pharmaceuticals and drug development.

Unique structure

Its unique structure contributes to its potential therapeutic properties.

Further analysis and research

The precise properties and applications of the compound would require further analysis and research.

Development of new medications

It demonstrates potential for use in the development of new medications and therapeutic treatments.

Upstream product

• 1603-79-8 phenylglyoxylic acid ethyl ester 
• 19833-96-6 2-Cyclopentyl-2-hydroxy-2-phenylacetic acid methyl ester 
• 1619-34-7 3-quinuclidinol 
• 16098-80-9 2-cyclopentyl-2-hydroxy-2-phenylacetic acid ethyl ester 

Relevant academic research and scientific papers

Synthesis and crystal structure of quinuclidin-3-yl 2-cyclopentyl-2- hydroxy-2-phenylacetate

Quinuclidin-3-yl 2-cyclopentyl-2-hydroxy-2-phenylacetate, a more effective the muscarinic receptor antagonist, was synthesised and its crystal structure was first elucidated by X-ray crystallography.

Analogues of 3-Quinuclidinyl Benzilate

A number of analogues of 3-quinuclidinyl benzilate (QNB) have been synthesized and their affinities to muscarinic receptor from rat or dog ventricular muscle measured.We have determined that the muscarinic receptor can to a different degree accomodate either a halogen in the ortho, meta, or para position of one phenyl ring or the repalcement of one phenyl ring with an alkyl group.Our in vitro competition studies show that the affinities lie within a 270-fold range, from the highest affinity compound, 3-quinuclidinyl α-hydroxy-α-cyclopentylphenylacetate (2), to the lowest affinity compound, 3-quinuclidinyl α-hydroxy-α-2-propargylphenylacetate (11).