Air & Water Reactions
Insoluble in water.
This material may be used as an epoxy resin reactive
diluent, as a component of epoxy coating systems, and as an
ingredient in alkyl resins to modify film properties. Improved
chemical resistance, weatherability, film hardness, and acid
number control are the properties enhanced in epoxy resin
applications by the use of this material.
Clear yellow liquid.
GLYCIDYL NEODECANOATE, MIXTURE OF BRANCHED ISOMERS reacts vigorously with strong oxidizing agents and strong Lewis and mineral acids. Reacts with considerable heat release with many curing agents.
The mutagenic activity of glycidyl
ester of neodecanoic acid was investigated in cultures of
S. typhimutium TA98, TA100, TA102, TA1535, TA1537, and
TA1538; E. coli WP2 and WP2 uvr A; and in cultures of
S. cerevisiae JD1, both with and without the incorporation of
rat liver microsomal enzymes. The results
indicated that glycidyl ester of neodecanoic acid induced an
increase in mutation frequency only after metabolic activation
in Salmonella strains TA100, TA1535, and TA1538. The
mutation frequency was within the spontaneous frequency
range in the absence of S9 fractions for these strains; however,
in some experiments weak responses were observed in the
absence of S9. In TA98, TA102, TA1537, and
TA1538, there was no increase in mutation frequency either
with or without S9. There was no increase in gene mutation
and frequency in either of the E. coli strains with or without
activation. Similarly, in Saccharomyces no changes in gene
conversion frequency were reported. In general, no significant
effects were detected below 100mg of material per plate,
suggesting that the mutagenic activity was relatively weak.
The bacterial results indicate thatmutagenicity was expressed
by both base-pair substitution and frameshift mechanisms.
In other studies, monolayer slides of cultures of rat liver
(RL1) cells were exposed to culture medium containing
glycidyl ester of neodecanoic acid, and after 24 h incubation,
the slides were processed for metaphase chromosome analysis
. In the RL1 cells, NAGE induced a low frequency
of chromatid aberrations at concentrations just below the
cytotoxic dose (50 mg/mL).
The glycidyl ester of neodecanoic acid (NAGE) is produced
by the reaction of neodecanoic acid with epichlorohydrin in
the presence of base.
GLYCIDYL NEODECANOATE, MIXTURE OF BRANCHED ISOMERS is probably combustible.