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267647-77-8

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267647-77-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 267647-77-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,7,6,4 and 7 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 267647-77:
(8*2)+(7*6)+(6*7)+(5*6)+(4*4)+(3*7)+(2*7)+(1*7)=188
188 % 10 = 8
So 267647-77-8 is a valid CAS Registry Number.

267647-77-8Downstream Products

267647-77-8Relevant articles and documents

Novel guanidine-Based inhibitors of inosine monophosphate dehydrogenase

Iwanowicz, Edwin J.,Watterson, Scott H.,Liu, Chunjian,Gu, Henry H.,Mitt, Toomas,Leftheris, Katerina,Barrish, Joel C.,Fleener, Catherine A.,Rouleau, Katherine,Sherbina,Hollenbaugh, Diane L.

, p. 2931 - 2934 (2007/10/03)

A series of novel guanidine-based small molecule inhibitors of inosine monophosphate dehydrogenase (IMPDH) was explored. IMPDH catalyzes the rate determining step in guanine nucleotide biosynthesis and is a target for anticancer, immunosuppressive and antiviral therapy. The synthesis and the structure-activity relationships (SARs), derived from in vitro studies, for this new series of inhibitors is given.

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