267648-19-1

Basic information

• Product Name: 1-(2-methoxy-4-nitrophenyl)-1H-1,2,4-triazole
• Synonyms: 1-(2-methoxy-4-nitrophenyl)-1H-1,2,4-triazole
• CAS NO: 267648-19-1
• Molecular Weight: 220.188
• Mol File: 267648-19-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1-(2-methoxy-4-nitrophenyl)-1H-1,2,4-triazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-methoxy-4-nitrophenyl)-1H-1,2,4-triazole(267648-19-1)
• EPA Substance Registry System: 1-(2-methoxy-4-nitrophenyl)-1H-1,2,4-triazole(267648-19-1)

Safety Data

• Hazardous Substances Data: 267648-19-1(Hazardous Substances Data)

Upstream product

• 288-88-0 1,2,4-Triazole 
• 1009-36-5 2-chloro-5-nitroanisole 
• 454-16-0 1-fluoro-2-methoxy-4-nitrobenzene 
• 77337-82-7 1-bromo-2-methoxy-4-nitrobenzene 

Relevant articles and documents

Discovery, Structure-Activity Relationships, and in Vivo Evaluation of Novel Aryl Amides as Brain Penetrant Adaptor Protein 2-Associated Kinase 1 (AAK1) Inhibitors for the Treatment of Neuropathic Pain

Effective treatment of chronic pain, in particular neuropathic pain, without the side effects that often accompany currently available treatment options is an area of significant unmet medical need. A phenotypic screen of mouse gene knockouts led to the d

CATHEPSIN K INHIBITOR AND APPLICATION THEREOF

The invention relates to capthepsin K inhibitors and uses thereof, specifically relates to a class of compounds having the formula (I) which are used for treating or preventing cathepsin dependent diseases or conditions, specifically, wherein the cathepsin is capthepsin K. The compounds and compositions thereof can be used as bone resorption inhibitors for the treatment of associated diseases.

Inhibitors of inosine monophosphate dehydrogenase: SARs about the N-[3-methoxy-4-(5-oxazolyl)phenyl moiety

The first reported structure-activity relationships (SARs) about the N-[3-methoxy-4-(5-oxazolyl)phenyl moiety for a series of recently disclosed inosine monophosphate dehydrogenase (IMPDH) inhibitors are described. The syntheses and in vitro inhibitory values for IMPDH II, and T-cell proliferation (for select analogues) are given.