267653-10-1Relevant academic research and scientific papers
Synthesis of cyclopeptide alkaloids by cyclooligomerization of dipeptidyl oxazolines
Wipf, Peter,Miller, Chris P,Grant, Charsetta M
, p. 9143 - 9150 (2000)
Cyclodehydration of Cbz-valylthreonine methyl esters with Burgess reagent provides access to cis- and trans-oxazoline segments for cyclooligomerization reactions. The ratio of 12-, 18-, 24-, and larger-ring macrocycles obtained in this process is kinetica
Synthesis of functionalized oxazolines and oxazoles with DAST and Deoxo-Fluor.
Phillips,Uto,Wipf,Reno,Williams
, p. 1165 - 1168 (2007/10/03)
[formula: see text] A mild and highly efficient cyclization of beta-hydroxy amides to oxazolines is described using DAST and Deoxo-Fluor reagents. A one-pot protocol for the synthesis of oxazoles from beta-hydroxy amides is also presented.
