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α-(4-methoxyphenyl)-α-phenyl-5-pyrimidinemethanol is a complex organic compound with the molecular formula C17H17N2O2. It is characterized by a pyrimidine ring, which is a six-membered heterocyclic aromatic ring containing four carbon atoms and two nitrogen atoms. The compound features a 4-methoxyphenyl group, which is a phenyl ring (a six-carbon ring with alternating double bonds) substituted with a methoxy group (-OCH3) at the 4-position. Additionally, it has a phenyl group attached to the α-carbon of the pyrimidine ring. The molecule also contains a hydroxyl group (-OH) attached to the α-carbon, making it a methanol derivative. α-(4-methoxyphenyl)-α-phenyl-5-pyrimidinemethanol is known for its potential applications in the synthesis of pharmaceuticals and agrochemicals, particularly as a building block for the development of new drugs.

26766-32-5

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26766-32-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 26766-32-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,6,7,6 and 6 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 26766-32:
(7*2)+(6*6)+(5*7)+(4*6)+(3*6)+(2*3)+(1*2)=135
135 % 10 = 5
So 26766-32-5 is a valid CAS Registry Number.

26766-32-5Downstream Products

26766-32-5Relevant academic research and scientific papers

Biological evaluation of 5-substituted pyrimidine derivatives as inhibitors of brassinosteroid biosynthesis

Wang, Jing-Ming,Asami, Tadao,Yoshida, Shigeo,Murofushi, Noboru

, p. 817 - 822 (2007/10/03)

A series of 5-substituted pyrimidine derivatives was synthesized, and their ability to inhibit brassinosteroid biosynthesis was tested. The biological activity of these compounds was evaluated by the cress stem elongation method. Among the synthesized com

Aromatase Inhibition by 5-Substituted Pyrimidines and Dihydropirimidines

Taylor, Harold M.,Jones, C. David,Davenport, James D.,Hirsch, Kenneth S.,Kress, T.J.,Weaver, Dix

, p. 1359 - 1365 (2007/10/02)

The inhibition of estrogen biosynthesis has been suggested to be an effective treatment of hormone-dependent diseases, particularly breast cancer.Several series of 5-substituted pyrimidine derivatives have been synthesized and tested for their ability to inhibit the enzyme aromatase (estrogen synthetase).Compounds were evaluated in an in vitro assay that measured the inhibition of rat ovarian microsomal aromatase activity.Greatest inhibitory activity was achieved in the cases of diarylpyrimidinemethanols and diarylpyrimidinyl methanes which were substituted in the 4- and 4'-positions with electron-withdrawing substituents, particularly Cl.

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