267901-39-3

Basic information

• Product Name: 2-Propynoic acid, 3-phenyl-, 4-(1,1-dimethylethyl)phenyl ester
• CAS NO: 267901-39-3
• Molecular Formula: C19H18O2
• Molecular Weight: 278.351
• Mol File: 267901-39-3.mol

Chemical Properties

• CAS DataBase Reference: 2-Propynoic acid, 3-phenyl-, 4-(1,1-dimethylethyl)phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propynoic acid, 3-phenyl-, 4-(1,1-dimethylethyl)phenyl ester(267901-39-3)
• EPA Substance Registry System: 2-Propynoic acid, 3-phenyl-, 4-(1,1-dimethylethyl)phenyl ester(267901-39-3)

Safety Data

• Hazardous Substances Data: 267901-39-3(Hazardous Substances Data)

Upstream product

• 98-54-4 para-tert-butylphenol 
• 2216-94-6 phenylpropynoic acid ethyl ester 
• 637-44-5 phenylpropyolic acid 

Relevant articles and documents

Visible-light initiated oxidative cyclization of phenyl propiolates with sulfinic acids to coumarin derivatives under metal-free conditions

A visible-light initiated oxidative cyclization of phenyl propiolates with sulfinic acids has been developed. The arylsulfonylation of alkynes was performed at room temperature under metal-free conditions to generate coumarin derivatives with wide functio

Chlorinative Cyclization of Aryl Alkynoates Using NCS and 9-Mesityl-10-methylacridinium Perchlorate Photocatalyst

In a chlorinative cyclization, Mes-Acr-MeClO4 acted as a visible-light photocatalyst to obtain 3-chlorocoumarins from aryl alkynoates and N-chlorosuccinimide (NCS). The radical initiated reaction proceeded in a cascading manner via Cl- addition to alkynoa

Ynamide-Mediated Intermolecular Esterification

An ynamide-mediated one-pot, two-step intermolecular esterification via the condensation of carboxylic acids with nucleophilic hydroxyl species was reported. A broad substrate scope with respect to carboxylic acids, alcohols, and phenols was observed. The α-acyloxyenamide intermediates formed by the addition of carboxylic acids to ynamides proved to be effective acylating reagents for the esterification of alcohol and phenol derivatives with the assistance of base catalysis. Notably, the racemization of the α-chiral center of carboxylic acids can be avoided.

Photoredox-Catalyzed Cascade Radical Cyclization of Ester Arylpropiolates with CF3SO2Cl to Construct 3-Trifluoromethyl Coumarin Derivatives

We report a highly efficient method to construct 3-trifluoromethyl coumarins using CF3SO2Cl as the trifluoromethyl radical source with ester 3-arylpropiolates. The reaction incorporated a cascade cyclization/dearomatization/ester mig

Visible-light photoredox catalyzed cyclization of aryl alkynoates for the synthesis of trifluoromethylated coumarins

A strategy for the synthesis of coumarin derivatives via visible-light photoredox catalysis has been developed using fac-Ir(ppy)3 as the photocatalyst under mild conditions. Trifluoromethanesulfonyl chloride is utilized as the trifluoromethylat

Visible-light-mediated radical cascade reaction: Synthesis of 3-bromocoumarins from alkynoates

A visible-light-mediated radical addition of alkynoates to generate 3-bromocoumarins by using N-bromosuccinimide as the bromo source has been accomplished. This procedure provides a bromo radical addition/spirocyclization/ester migration cascade reaction

Visible-Light-Promoted Dual C-C Bond Formations of Alkynoates via a Domino Radical Addition/Cyclization Reaction: A Synthesis of Coumarins

A visible-light-promoted, mild, and direct difunctionalization of alkynoates has been accomplished. This procedure provides a new strategy toward synthesis of the coumarin core structure by photoredox-mediated oxidation to generate the α-oxo radical, whic

Synthesis of 3-Sulfenylated Coumarins: BF3·Et2O-Mediated Electrophilic Cyclization of Aryl Alkynoates Using N-Sulfanylsuccinimides

A simple and efficient metal-free sulfenylation/cyclization of aryl alkynoates has been developed, obtaining various 3-sulfenylated coumarins in moderate to excellent yields. In the presence of BF3·Et2O, the stable and readily access

FeCl3-catalyzed alkenylation of simple arenes with aryl-substituted alkynes

An addition of electron-rich arenes to aryl-substituted alkynes to form 1,1-diaryl alkenes is carried out in the presence of FeCl3 as catalyst under mild conditions.

New Method for Preparation of Coumarins and Quinolinones via Pd-Catalyzed Intramolecular Hydroarylation of C-C Triple Bonds

A new and general method has been developed for preparation of coumarins and quinolinones by intramolecular hydroarylation of alkynes. Various aryl alkynoates and alkynanilides undergo fast intramolecular reaction at room temperature in the presence of a