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Pregn-1,4-diene-3,20-dione, 11,17-dihydroxy-21-(phosphonooxy)-, monosodium salt, (11beta)- is a complex organic compound with the chemical formula C21H29O7PNa. It is a derivative of pregnane, a steroid with a cyclopentane ring fused to a perhydrophenanthrene structure. This specific compound features two hydroxyl groups at the 11 and 17 positions, a phosphonooxy group at the 21 position, and a sodium ion, which makes it a monosodium salt. It is synthesized for use as a pharmaceutical agent, particularly in the treatment of certain hormonal imbalances and conditions related to the reproductive system. The compound's structure and functional groups give it specific biological activities, making it a valuable component in medical therapies.

2681-16-5

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2681-16-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2681-16-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,6,8 and 1 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 2681-16:
(6*2)+(5*6)+(4*8)+(3*1)+(2*1)+(1*6)=85
85 % 10 = 5
So 2681-16-5 is a valid CAS Registry Number.
InChI:InChI=1/C21H29O8P.Na/c1-19-7-5-13(22)9-12(19)3-4-14-15-6-8-21(25,17(24)11-29-30(26,27)28)20(15,2)10-16(23)18(14)19;/h5,7,9,14-16,18,23,25H,3-4,6,8,10-11H2,1-2H3,(H2,26,27,28);/q;+1/p-1

2681-16-5Upstream product

2681-16-5Downstream Products

2681-16-5Relevant academic research and scientific papers

Process for producing high-standard prednisolone sodium phosphate

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Paragraph 0008, (2016/11/14)

The invention discloses a process for producing high-standard prednisolone sodium phosphate, and belongs to the field of chemistry. The process adopts prednisolone phosphate as a raw material, and comprises the following steps: A, adding prednisolone phosphate into pure water, stirring and adjusting the temperature to 20-40 DEG C, wherein the pure water volume (unit: milliliter) is 5-10 times of that of prednisolone phosphate (unit: g); B, dropwise adding a sodium hydroxide solution in the state of monitoring the pH value, and stirring the reaction system during adding until the system pH is 9.5, wherein the temperature of the system is controlled to be 25-35 DEG C during adding; C, filtering the reactant when the pH value becomes constant, and drying the filtrate after filtration to obtain high-standard prednisolone sodium phosphate. The process provided by the invention is simple and easy to implement, and is suitable for being applied to the production of high-standard prednisolone sodium phosphate.

Method for reducing or preventing transplant rejection in the eye and intraocular implants for use therefor

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, (2008/06/13)

Methods for reducing or preventing transplant rejection in the eye of an individual are described, comprising: a) performing an ocular transplant procedure; and b) implanting in the eye a bioerodible drug delivery system comprising an immunosuppressive agent and a bioerodible polymer.

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