268209-75-2Relevant academic research and scientific papers
Enzyme-cleavable linkers for peptide and glycopeptide synthesis
Maltman, Beatrice A.,Bejugam, Mallesham,Flitsch, Sabine L.
, p. 2505 - 2507 (2005)
Hydroxymethylphenoxy linkers that are commonly used in solid phase peptide synthesis are surprisingly susceptible to efficient cleavage by the protease chymotrypsin with a broad range of amino acid residues being tolerated at the scissile bond; this enzyme-cleavable linker system has been applied to peptide and glycopeptide synthesis. The Royal Society of Chemistry 2005.
