268219-99-4

Basic information

• Product Name: 3-(4-METHOXY-BENZYLSULFANYL)-3-METHYL-BUTYRIC ACID
• Synonyms: 3-(4-METHOXY-BENZYLSULFANYL)-3-METHYL-BUTYRIC ACID;BETA-S-(4-METHOXYBENZYLMERCAPTO)-ISOVALERIC ACID;b-S-(4-Methoxybenzylmercapto)isovaleric acid;S-(4-Methoxybenzyl)-deaMino-penicillaMine;β-S-(4-Methoxybenzylmercapto)isovaleric acid;β-S-(4-Methoxybenzylmercapto)isovaleric acid≥ 99% (TLC)
• CAS NO: 268219-99-4
• Molecular Formula: C₁₃H₁₈O₃S
• Molecular Weight: 254.35
• Mol File: 268219-99-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-(4-METHOXY-BENZYLSULFANYL)-3-METHYL-BUTYRIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-METHOXY-BENZYLSULFANYL)-3-METHYL-BUTYRIC ACID(268219-99-4)
• EPA Substance Registry System: 3-(4-METHOXY-BENZYLSULFANYL)-3-METHYL-BUTYRIC ACID(268219-99-4)

Safety Data

• Hazardous Substances Data: 268219-99-4(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Upstream product

• 924-50-5 Methyl 3,3-dimethylacrylate 
• 6258-60-2 p-methoxybenzylmercaptan 
• 541-47-9 3-Methylbutenoic acid 

Relevant articles and documents

CALICHEAMICIN DERIVATIVES AND ANTIBODY DRUG CONJUGATES THEREOF

The present invention is directed to novel calicheamicin derivatives useful as payloads in antibody-drug-conjugates (ADC's), and to payload-linker compounds and ADC compounds comprising the same; to pharmaceutical compositions comprising the same and to methods for using the same to treat pathological conditions such as cancer.

INTERMEDIATES AND METHODS FOR SYNTHESIZING CALICHEAMICIN DERIVATIVES

The present invention relates to intermediates of Formula (I) and to methods of synthesizing and purifying calicheamicin derivatives.