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L-malic acid, also known as hydroxysuccinic acid, is a naturally occurring organic compound that plays a crucial role in the citric acid cycle, a key metabolic pathway in cellular respiration. It is a white crystalline solid with a tart taste and is found in various fruits, particularly apples and grapes. L-malic acid has various applications, including food and beverage industry as a flavoring agent, in skincare products for exfoliation, and as a dietary supplement for energy enhancement. Ammonium L-malate is the ammonium salt of L-malic acid, formed by the reaction of L-malic acid with ammonia. It is a white crystalline powder that is soluble in water and is used in various applications, such as a buffer in pharmaceuticals, a flavor enhancer in food products, and a component in certain dietary supplements. Both L-malic acid and ammonium L-malate are important compounds with diverse uses in different industries, showcasing their versatility and significance in modern applications.

2689-91-0

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2689-91-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2689-91-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,6,8 and 9 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 2689-91:
(6*2)+(5*6)+(4*8)+(3*9)+(2*9)+(1*1)=120
120 % 10 = 0
So 2689-91-0 is a valid CAS Registry Number.

2689-91-0Upstream product

2689-91-0Downstream Products

2689-91-0Relevant academic research and scientific papers

NOVEL PROCESS

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Page/Page column 24-25, (2011/09/30)

The present invention relates to an improved process for preparing acid addition salts of sunitinib, in particular sunitinib (2S)-2-hydroxybutanedioate (I). The invention also relates to compositions comprising sunitinib acid addition salts such as sunitinib (2S)-2- hydroxybutanedioate (I) and to the use of said compositions in the treatment of disease.

NOVEL PROCESS

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Page/Page column 34, (2011/11/01)

The present invention relates to novel processes for the preparation of sunitinib and salts thereof, in particular sunitinib (2S)-2-hydroxybutanedioate. The invention further relates to novel intermediates, their use in the preparation of sunitinib or salts thereof and to processes for the preparation of said intermediates. The invention also relates to compositions comprising sunitinib or its pharmaceutically acceptable salts.

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