26893-64-1Relevant academic research and scientific papers
Fujiwara-Moritani Reaction of Weinreb Amides using a Ruthenium-Catalyzed C-H Functionalization Reaction
Das, Riki,Kapur, Manmohan
, p. 1505 - 1512 (2015)
The ruthenium-catalyzed Fujiwara-Moritani reaction (oxidative-Heck reaction) of Weinreb amides is reported herein. The reaction affords exclusively ortho-C-H olefination products, has excellent substrate scope and tolerates halogen functionalities, which increase the synthetic utility of the method. A variety of activated olefins as well as styrenes can be employed as coupling partners. RU sure? The ruthenium-catalyzed Fujiwara-Moritani reaction (oxidative-Heck reaction) of Weinreb amides has been reported. The reaction affords exclusively ortho-C-H olefination products, has excellent substrate scope and tolerates halogen functionalities; this increases the synthetic utility of the method.
