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Thiazolo[4,5-g]quinoline, also known as 1,2,4-thiadiazolo[4,5-g]quinoline, is a heterocyclic compound consisting of a quinoline ring fused to a thiazolo ring. This organic molecule is characterized by the presence of a sulfur atom in the thiazole ring, which imparts unique chemical properties and reactivity. It is an important building block in the synthesis of various pharmaceuticals and agrochemicals due to its potential biological activities. The compound is typically synthesized through cyclization reactions involving appropriate precursors, such as 2-aminobenzothiazole derivatives. Thiazolo[4,5-g]quinolines have been found to exhibit a range of biological activities, including anti-inflammatory, antimicrobial, and anticancer properties, making them a subject of interest in medicinal chemistry research.

269-25-0

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269-25-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 269-25-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 2,6 and 9 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 269-25:
(5*2)+(4*6)+(3*9)+(2*2)+(1*5)=70
70 % 10 = 0
So 269-25-0 is a valid CAS Registry Number.

269-25-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name [1,3]thiazolo[4,5-g]quinoline

1.2 Other means of identification

Product number -
Other names Thiazolo[4,5-g]quinoline(8CI,9CI)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:269-25-0 SDS

269-25-0Downstream Products

269-25-0Relevant academic research and scientific papers

Quinoline synthesis by improved Skraup-Doebner-Von Miller reactions utilizing acrolein diethyl acetal

Ramann, Ginelle A.,Cowen, Bryan J.

, p. 6436 - 6439 (2015)

A robust synthetic method has been developed as an improvement to the venerable Skraup-Doebner-Von Miller reaction providing access to various quinoline products. The straightforward procedure utilizes acrolein diethyl acetal as a three-carbon annulation partner with aniline substrates in a monophasic, organic solvent-free reaction medium. Differentially substituted aniline precursors were found to be compatible with the reaction conditions and the corresponding quinoline products are isolated in moderate to good yields.

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