26903-39-9

Basic information

• Product Name: (all-E)-20,20'-dinor-β,β-carotene
• CAS NO: 26903-39-9
• Molecular Weight: 508.831
• Mol File: 26903-39-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (all-E)-20,20'-dinor-β,β-carotene(CAS DataBase Reference)
• NIST Chemistry Reference: (all-E)-20,20'-dinor-β,β-carotene(26903-39-9)
• EPA Substance Registry System: (all-E)-20,20'-dinor-β,β-carotene(26903-39-9)

Safety Data

• Hazardous Substances Data: 26903-39-9(Hazardous Substances Data)

Upstream product

• 859991-32-5 optically inactive 3,16-dimethyl-1,18-bis-(2,6,6-trimethyl-cyclohex-1-enyl)-octadeca-2,4,6,12,14,16-hexaen-9-yne-8,11-diol 
• 3049-34-1 (2E,4E,6E)octa-2,4,6-triene-1,8-dial 
• 53282-28-3 [(2E,4E)-3-methyl-5-(2,6,6-trimethylcyclohex-1-en-1-yl)penta-2,4-dienyl]triphenylphosphonium chloride 

Relevant articles and documents

The substrate specificity of β,β-carotene 15,15′-monooxygenase

The synthesis of several substrate analogues of the enzyme β,β-carotene 15,15′-monooxygenase is reported. The substrate specificity of enriched enzyme fractions isolated from chicken intestinal mucosa was investigated. Regarding substrate binding/cleavage, these experiments demonstrate that i) any deviation from the rod-like β,β-carotene structure is not tolerated, ii) one 'natural', unsubstituted β-ionone ring is required, iii) the position and presence of the Me groups attached to the polyene chain is significant. These results suggest a hydrophobic barrel-like substrate binding site in which the protein's amino acid residues through interaction with the Me groups, direct the central C=C bond in binding distance to the active site's metal-oxo center, supporting the unique regiospecificity of cleavage to retinal (provitamin A).