2691-16-9Relevant academic research and scientific papers
Addition of arylboronic acids to arylpropargyl alcohols en route to indenes and quinolines
Panteleev, Jane,Huang, Richard Y.,Lui, Erica K. J.,Lautens, Mark
supporting information; experimental part, p. 5314 - 5317 (2011/12/01)
A regio- and stereoselective rhodium-catalyzed synthesis of trisubstituted allylic alcohols is described. The utility of these synthons is demonstrated in a convenient synthesis of indenes and quinolines.
CHLORO- AND IODOTRIMETHYLSILANE-ACTIVATED ADDITIONS OF ORGANOCOPPER COMPOUNDS TO ENONES AND ENOATES
Bergdahl, Mikael,Lindstedt, Eva-Lotte,Nilsson, Martin,Olsson, Thomas
, p. 2055 - 2062 (2007/10/02)
Organocopper compounds add to enones and enoates in the presence of chloromethylsilane in ether giving the conjugate adducts in preparatively usefu yields via the silyl enol ethers.Presence of lithium iodide is important and excess of chlorotrimethylsilane accelerates the reactions.The combination of organocopper compound, iodotrimethylsilane and dimethyl sulfide gave faster reactions and very high yields, particularly in dichloromethane, where the reaction mixtures gradually became homogeneous.
