26919-42-6

Basic information

• Product Name: 3,5-DIMETHYL-1-ADAMANTANEMETHANOL
• Synonyms: 3,5-DIMETHYLADAMANTANE-1-METHANOL, 97%;3,5-DIMETHYL-1-ADAMANTANEMETHANOL, 98%(GC);3,5-Dimethyl-1-(hydroxymethyl)adamantane, 3,5-Dimethyltricyclo[3.3.1.13,7]decane-1-methanol;3,5-Dimethyl-1-(hydroxymethyl)adamantane;3,5-Dimethyltricyclo[3.3.1.13,7]decane-1-methanol;(3,5-Dimethyladamantan-1-yl)methanol
• CAS NO: 26919-42-6
• Molecular Formula: C₁₃H₂₂O
• Molecular Weight: 194.31318
• Product Categories: Adamantanes;Alcohols;Building Blocks;C11 to C30+;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds
• Mol File: 26919-42-6.mol
• Article Data: 4

Chemical Properties

• Melting Point: 58-62 °C
• Boiling Point: 115 °C / 3mmHg
• Flash Point: 121.4±8.6℃
• Appearance: White/Solid
• Density: 1.066±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 0.00124mmHg at 25°C
• Refractive Index: 1.544
• Solubility: soluble in Methanol
• PKA: 15.04±0.10(Predicted)
• CAS DataBase Reference: 3,5-DIMETHYL-1-ADAMANTANEMETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-DIMETHYL-1-ADAMANTANEMETHANOL(26919-42-6)
• EPA Substance Registry System: 3,5-DIMETHYL-1-ADAMANTANEMETHANOL(26919-42-6)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 26919-42-6(Hazardous Substances Data)

Usage

General Description

3,5-DIMETHYL-1-ADAMANTANEMETHANOL is a chemical compound with the molecular formula C14H23O. It is a white crystalline solid that is used in the synthesis of pharmaceuticals and other organic compounds. This chemical is a derivative of adamantane, a hydrocarbon with a unique cage-like structure. The presence of two methyl groups at positions 3 and 5 on the adamantane ring gives 3,5-DIMETHYL-1-ADAMANTANEMETHANOL its distinct properties and reactivity. It is commonly used as an intermediate in the production of various drugs and as a building block in organic synthesis. Additionally, its unique structure and reactivity make it an interesting target for research in the field of organic chemistry.

InChI:InChI=1/C13H22O/c1-11-3-10-4-12(2,6-11)8-13(5-10,7-11)9-14/h10,14H,3-9H2,1-2H3

Upstream product

• 201230-82-2 carbon monoxide 
• 941-37-7 3,5-dimethyl-1-bromoadamantane 
• 702-79-4 1,3-dimethyladamantane 
• 50-00-0 formaldehyd 
• 80405-15-8 3,5-dimethyl-1-iodoadamantane 
• 14670-94-1 3,5-dimethyl-1-adamantanecarboxylic acid 

Downstream Products

• 702-79-4 1,3-dimethyladamantane 
• 1233222-34-8 C₂₉H₃₆N₂O₆ 
• 58727-83-6 3,5-dimethyladamantane-1-carboxaldehyde 
• 14670-94-1 3,5-dimethyl-1-adamantanecarboxylic acid 
• 40430-57-7 3, 5-dimethyl-1-adamantyl methyl ketone 

Relevant articles and documents

Radical addition of alkyl halides to formaldehyde in the presence of cyanoborohydride as a radical mediator. A new protocol for hydroxymethylation reaction

Hydroxymethylation of alkyl halides was achieved using paraformaldehyde as a radical C1 synthon in the presence of tetrabutylammonium cyanoborohydride as a hydrogen source. The reaction proceeds via a radical chain mechanism involving an alkyl radical addition to formaldehyde to form an alkoxy radical, which abstracts hydrogen from a hydroborate anion.

ADAMANTYGLYCINE-BASED INHIBITORS OF DIPEPTIDYL PEPTIDASE IV AND METHODS

Compounds are provided having the formula (I) [Chemical Structure] wherein: n is 0, 1 or 2; m is 0, 1 or 2; the sum of n + m less then or equal to 2; the dashed bonds forming a cyclopropyl ring can only be present when Y is CH; X is H or CN; Y is CH, CH2, CHF, CF2, O, S, SO, or SO2; and A is adamantyl. Further provided are methods of using such compounds for the treatment of diabetes and related diseases, and to pharmaceutical compositions containing such compounds.