269396-56-7 Usage
Uses
Used in Pharmaceutical Research and Development:
BOC-(R)-3-AMINO-4-(3,4-DICHLORO-PHENYL)-BUTYRIC ACID is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic applications.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, BOC-(R)-3-AMINO-4-(3,4-DICHLORO-PHENYL)-BUTYRIC ACID is employed as a structural component in the design and synthesis of bioactive molecules, leveraging its unique properties to enhance drug efficacy and selectivity.
Used in Chemical Research:
BOC-(R)-3-AMINO-4-(3,4-DICHLORO-PHENYL)-BUTYRIC ACID is utilized as a research compound to explore its chemical properties and reactivity, contributing to the advancement of chemical knowledge and the creation of novel chemical entities.
Used in Drug Development:
BOC-(R)-3-AMINO-4-(3,4-DICHLORO-PHENYL)-BUTYRIC ACID is used as a precursor in drug development for its potential to be incorporated into new pharmaceuticals, offering a pathway to improved treatments and therapies.
Used in Chemical Synthesis:
In chemical synthesis, BOC-(R)-3-AMINO-4-(3,4-DICHLORO-PHENYL)-BUTYRIC ACID is used as a reactant or building block for creating complex organic molecules, taking advantage of its functional groups for further chemical transformations.
Check Digit Verification of cas no
The CAS Registry Mumber 269396-56-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,9,3,9 and 6 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 269396-56:
(8*2)+(7*6)+(6*9)+(5*3)+(4*9)+(3*6)+(2*5)+(1*6)=197
197 % 10 = 7
So 269396-56-7 is a valid CAS Registry Number.
InChI:InChI=1/C15H19Cl2NO4/c1-15(2,3)22-14(21)18-10(8-13(19)20)6-9-4-5-11(16)12(17)7-9/h4-5,7,10H,6,8H2,1-3H3,(H,18,21)(H,19,20)/t10-/m1/s1
269396-56-7Relevant academic research and scientific papers
Discovery of potent and selective β-homophenylalanine based dipeptidyl peptidase IV inhibitors
Xu, Jinyou,Ok, Hyun O.,Gonzalez, Edward J.,Colwell Jr., Lawrence F.,Habulihaz, Bahanu,He, Huaibing,Leiting, Barbara,Lyons, Kathryn A.,Marsilio, Frank,Patel, Reshma A.,Wu, Joseph K.,Thornberry, Nancy A.,Weber, Ann E.,Parmee, Emma R.
, p. 4759 - 4762 (2007/10/03)
Modification of in-house screening lead β-aminoacyl proline 8 gave an equipotent thiazolidide 9. Extensive SAR studies on the phenyl ring of 9 led to the discovery of a novel series of potent and selective DP-IV inhibitors. Introduction of a fluorine at the 2-position proved to be crucial for the potency of this series. The 2,5-difluoro (22q) and 2,4,5-trifluoro (22t) analogues were potent inhibitors of DP-IV (IC50 = 270, 119 nM, respectively).
