26944-71-8

Usage

Uses

Used in Organic Synthesis:
2-BROMO-6-HYDRAZINYLPYRIDINE is used as a reagent in organic synthesis for the preparation of various pharmaceuticals and agrochemicals. Its unique structure allows it to participate in a range of chemical reactions, contributing to the development of new and effective compounds for medical and agricultural applications.
Used in Dye and Pigment Production:
In the chemical industry, 2-BROMO-6-HYDRAZINYLPYRIDINE serves as an intermediate in the production of dyes and pigments. Its chemical properties enable it to be incorporated into the manufacturing process of colorants used in various applications, including textiles, plastics, and printing inks.
Safety Precautions:
Given its classification as a hazardous chemical, 2-BROMO-6-HYDRAZINYLPYRIDINE requires proper handling and storage to ensure the safety of workers and the environment. This includes adherence to safety protocols, the use of appropriate personal protective equipment, and secure storage conditions to prevent accidental exposure or contamination.

InChI:InChI=1/C5H6BrN3/c6-4-2-1-3-5(8-4)9-7/h1-3H,7H2,(H,8,9)

Upstream product

• 626-05-1 2,6-Dibromopyridine 
• 144100-07-2 2-bromo-6-fluoropyridine 
• 60-34-4 methylhydrazine 

Downstream Products

• 1028293-89-1 C₈H₁₀BrClN₄O 
• 20798-52-1 2-bromo-6-(2-cyclohexylidenehydrazinyl)pyridine 
• 1342811-05-5 C₁₇H₂₅BrN₄O₂ 
• 1342810-88-1 2-{4-[2-(6-bromopyridin-2-yl)hydrazineylidene]cyclohexyl}isoindoline-1,3-dione 
• 1342811-10-2 C₁₈H₁₈BrN₃O₂ 
• 1382805-38-0 4-((2,4-difluorophenyl)methoxy)-1-(9-methyl-5,7,8,9-tetrahydro-6H-pyrido[3',4':4,5]pyrrolo[2,3-b]pyridin-2-yl)pyridin-2(1H)-one 
• 1382805-37-9 4-((2,4-dichlorophenyl)methoxy)-1-(9-methyl-5,7,8,9-tetrahydro-6H-pyrido[3',4':4,5]pyrrolo[2,3-b]pyridin-2-yl)pyridin-2(1H)-one 
• 1438258-14-0 5-bromo-2-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)ethyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one 
• 1438258-15-1 2-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)ethyl)-5-morpholino-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one 
• 1699749-05-7 2-bromo-9H-pyrrolo[2,3-b:4,5-c']dipyridine 

Relevant academic research and scientific papers

Compound and application thereof

The invention provides a compound and application thereof. The compound has a structure as shown in a formula I, and is used as a material of an electron transport layer in an organic electroluminescent device. The organic electroluminescent device comprises a first electrode, a second electrode and an organic layer between the first electrode and the second electrode, wherein the organic layer contains any one or a combination of at least two of the compounds. The compound has relatively high electron injection and migration performance. When the compound is used as an electron transport layer material in an organic electroluminescent device, the luminous efficiency of the device can be improved, and the starting voltage of the device can be reduced.

DIAGNOSTIC COMPOSITIONS FOR PET IMAGING, A METHOD FOR MANUFACTURING THE DIAGNOSTIC COMPOSITION AND ITS USE IN DIAGNOSTICS

The present application relates to a diagnostic composition comprising: a. a compound of Formula I, b. ethanol, c. water, and d. a hydroxycarboxylic acid, a salt of a hydroxycarboxylic acid or a mixture thereof. The diagnostic composition can be used in the selective detection of disorders and abnormalities associated with Tau aggregates such as Alzheimer's disease (AD) and other tauopathies, for example, using Positron Emission Tomography (PET). The present invention also relates to a method of preparing the claimed diagnostic composition.

NOVEL METHOD OF PREPARING AN IMAGING COMPOUND

The present invention relates to a novel method of preparing a compound of the formula I. Diagnostic compositions and their use in the selective detection of disorders and abnormalities associated with Tau aggregates such as Alzheimer's disease (AD) and other tauopathies, for example, using Positron Emission Tomography (PET) imaging are also disclosed.

AZACARBOLINE COMPOUNDS FOR THE DETECTION OF TAU AGGREGATES

The present invention relates to novel compounds of the formula (II) that can be employed in the selective Tau detection of disorders and abnormalities associated with Tau aggregates such as Alzheimer's disease and other tauopathies using Positron Emissio

NOVEL COMPOUNDS FOR THE TREATMENT, ALLEVIATION OR PREVENTION OF DISORDERS ASSOCIATED WITH TAU AGGREGATES

The present invention relates to novel compounds that can be employed in the treatment, alleviation or prevention of a group of disorders and abnormalities associated with Tau (Tubulin associated unit) protein aggregates including, but not limited to, Neu

COMPOUNDS FOR IMAGING TAU PROTEIN AGGREGATES

The present invention relates to novel compounds of the formula (I) that can be employed in the selective Tau detection of disorders and abnormalities associated with Tau aggregates such as Alzheimer's disease and other tauopathies using Positron Emission Tomography (PET) Imaging.

COMPOUNDS FOR IMAGING TAU PROTEIN AGGREGATES

The present invention relates to novel compounds of the formula (II) that can be employed in the selective Tau detection of disorders and abnormalities associated with Tau aggregates such as Alzheimer's disease and other tauopathies using Positron Emission Tomography (PET) Imaging.

Carbazole and Carboline Compounds for Use in the Diagnosis, Treatment, Alleviation or Prevention of Disorders Associated with Amyloid or Amyloid-Like Proteins

The present invention relates to novel compounds that can be employed in the diagnosis, treatment, alleviation or prevention of a group of disorders and abnormalities associated with amyloid proteins and amyloid-like proteins, such as Alzheimer's disease. Precursors for the preparation of the compounds according to the present invention are also provided.

DIHYDROPYRIDOPYRROLE DERIVATIVES AS TAU-PET-LIGANDS

The present invention relates to novel compounds of formula (I) that can be employed in the selective Tau detection of disorders and abnormalities associated with Tau aggregates such as Alzheimer's disease and other Tauopathies using Positron Emission Tom

A (3, 5 - double-trifluoromethyl pyrazolyl) pyridine derivative synthesis method

The invention discloses a method for synthesizing (3,5-bistrifluoromethylpyrazolyl)pyridine derivatives with potential bioactivity. The method comprises the following step: under heating conditions, carrying out substitution/cyclization/dehydration reaction on the raw material 2-bromopyridine derivatives with hydrazine hydrate and hexafluoroacetylacetone to synthesize the (3,5-bistrifluoromethylpyrazolyl)pyridine. Compared with the reported synthesis methods, the method disclosed by the invention has the advantages of accessible raw material, high synthesis efficiency, easy derivation of the product and the like.