26969-66-4

Basic information

• Product Name: POLY(DL-LACTIC ACID)
• Synonyms: POLY(DL-LACTIC ACID);Poly(DL-lacticacid)-mw20000-30000;poly(lactide)
• CAS NO: 26969-66-4
• Molecular Formula: C6H8O4
• Molecular Weight: 0
• Mol File: 26969-66-4.mol
• Article Data: 63

Chemical Properties

• Appearance: /
• CAS DataBase Reference: POLY(DL-LACTIC ACID)(CAS DataBase Reference)
• NIST Chemistry Reference: POLY(DL-LACTIC ACID)(26969-66-4)
• EPA Substance Registry System: POLY(DL-LACTIC ACID)(26969-66-4)

Safety Data

• Hazardous Substances Data: 26969-66-4(Hazardous Substances Data)

Upstream product

• 97-64-3 ethyl 2-hydroxypropionate 
• 79-33-4 L-Lactic acid 
• 10326-41-7 D-Lactic acid 
• 849585-22-4 LACTIC ACID 
• 4511-42-6 L,L-dilactide 
• 123-54-6 acetylacetone 
• 2216-51-5 (-)-menthol 
• 1071822-17-7 (6S)-3-methylene-6-methyl-1,4-dioxane-2,5-dione 
• 26680-10-4 3,6-dimethyl-1,4-dioxane-2,5-dione 
• 661-19-8 1-docosanol 
• 27871-49-4 (S)-Methyl lactate 
• 13076-19-2 (3R,6S)-3,6-dimethyl-1,4-dioxane-2,5-dione 
• 7440-31-5 stannane 
• 95-96-5 D,L-lactide 

Downstream Products

• 52183-00-3 1,1-diphenylpropane-1,2-diol 
• 106942-22-7 lactanilide 
• 958298-96-9 (N,N'-bis(2,6-diisopropylphenyl)(tert-butyl)amidinato)tin(II)(OCH(Me)C(O)OCH(Me)C(O)OCHMe₂) 
• 26680-10-4 3,6-dimethyl-1,4-dioxane-2,5-dione 
• 314069-33-5 (S)-2-hydroxy-propionic acid (S)-1-benzyloxycarbonyl-ethyl ester 
• 547-64-8 methyl lactate 
• 97-64-3 ethyl 2-hydroxypropionate 
• 616-09-1 n-propyl lactate 
• 57-55-6 propylene glycol 
• 2037-15-2 Methyl 2-(2-hydroxypropionyl)propionate 
• 4254-15-3 (S)-1,2-Propanediol 
• 4254-14-2 (2R)-propane-1,2-diol 
• 13076-19-2 (3R,6S)-3,6-dimethyl-1,4-dioxane-2,5-dione 

Relevant articles and documents

A study on highly concentrated lactic acid and the synthesis of lactide from its solution

Lactic acid is an important platform compound used as raw material for the production of lactide and polylactic acid. However, its concentration and composition distribution are not as simple as those of common compounds. In this work, the mass concentration distribution of highly concentrated lactic acid is determined by back titration. The components of highly concentrated lactic acid, crude lactide, and polymer after the reaction are analyzed by HPLC. Different concentrations of lactic acid solution were prepared for the synthesis of lactide and its content in the product was determined by 1H NMR analysis. We found that lactide is more easily produced from high-concentration lactic acid solution with which the condensed water is easier to release. Hence, the removal of condensed water is crucial to the formation of lactide, although it is not directly formed by esterification of two molecules of lactic acid.

SYNTHESIS METHOD AND DEVICE FOR RAPIDLY PRODUCING LACTIDE AT HIGH YIELD

The invention discloses a synthesis method and device for rapidly producing lactide at high yield. The method comprises: adding a single component of lactic acid or two components of lactic acid and catalyst, passing the mixture through a mixer to enter an oligomer preparation system, increasing a residence time through bottom circulation, synthesizing oligomeric lactic acid, and passing a gas-phase component through a rectification system. With the adoption of the device, the lactide is capable of being efficiently synthesized, crude lactide with a yield of 94% to 98% is capable of being obtained.

METHOD FOR SYNTHESIZING LACTIDE BY MEANS OF CATALYSIS OF LACTID ACID

The present invention relates to a method for the catalytic synthesis of lactide from lactic acid. The method relates to the synthesis of lactide from lactic acid under the catalysis of a zinc oxide nanoparticle aqueous dispersion as a catalyst. The present invention has four technical characteristics: I. the zinc oxide nanoparticle aqueous dispersion catalyst has a sufficient surface area, and the size of nanoparticles is merely 30-40 nm, providing a sufficient contact area between the substrate (lactic acid) and the catalyst; II. the new catalyst has a milder catalytic effect on polymerization, allowing the molecular weight distribution of a prepolymer within a range of 400-1500 g/mol, which is advantageous for depolymerization to proceed; III. the new catalyst is stable, thus avoiding oxidation or carbonization in a high temperature reaction; and IV. the new catalyst has a low toxicity and a small threat to human health.