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Tert-butyl 2-(2-(((benzyloxy)carbonyl)amino)propanamido)acetate is a complex organic compound with the molecular formula C18H26N2O6. It is a derivative of acetic acid, featuring a tert-butyl group, a benzyloxycarbonyl group, and a propaneamido moiety. tert-butyl 2-(2-(((benzyloxy)carbonyl)amino)propanamido)acetate is often used in peptide synthesis as a protecting group for the amino group, which is crucial for controlling the reactivity and selectivity of the peptide bonds during the synthesis process. The benzyloxycarbonyl (Z) group is a common protecting group that can be removed under mild acidic conditions, allowing for the controlled deprotection of the amino group. tert-butyl 2-(2-(((benzyloxy)carbonyl)amino)propanamido)acetate's structure and properties make it a valuable tool in the field of organic chemistry, particularly in the synthesis of complex peptides and other biomolecules.

2697-34-9

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2697-34-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2697-34-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,6,9 and 7 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 2697-34:
(6*2)+(5*6)+(4*9)+(3*7)+(2*3)+(1*4)=109
109 % 10 = 9
So 2697-34-9 is a valid CAS Registry Number.

2697-34-9Relevant academic research and scientific papers

CROSS-LINKED PYRROLOBENZODIAZEPINE DIMER (PBD) DERIVATIVE AND ITS CONJUGATES

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Page/Page column 137, (2020/01/31)

A novel cross-linked cytotoxic agents, pyrrolobenzo-diazepine dimer (PBD) derivatives, and their conjugates to a cell-binding molecule, a method for preparation of the conjugates and the therapeutic use of the conjugates.

CONJUGATION LINKERS CONTAINING 2,3-DIAMINOSUCCINYL GROUP

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Page/Page column 193, (2020/05/19)

Provided is a conjugate of a cytotoxic drug/molecule to a cell-binding molecule with a bis-linker (adual-linker) containing a 2, 3-diaminosuccinyl group. It also relates to preparation of the conjugate of a cytotoxic drug/molecule to a cell-binding molecule with the bis-linker, particularly when the drug having functional groups of amino, hydroxyl, diamino, amino-hydroxyl, dihydroxyl, carboxyl, hydrazine, aldehyde and thiol for conjugation with the bis-linker in a specific manner, as well as the therapeutic use of the conjugates.

CONJUGATION OF A CYTOTOXIC DRUG WITH BIS-LINKAGE

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Paragraph 0617-0619, (2020/01/08)

What provided is the conjugation of cytotoxic to a cell-binding molecule with a bis-linker(dual-linker) as shown in Formula (I). It provides bis-linkage methods of making a conjugate of a cytotoxic drug molecule to a cell-binding agent in a specific manner. It also relates to application of the conjugates for the treatment of a cancer, or an autoimmune disease, or an infectious disease.

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