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Fmoc-(R)-3-Amino-4-(2-cyano-phenyl)-butyric acid is a specialized chemical compound utilized in the field of peptide synthesis. It features a butyric acid backbone that is distinctively substituted with both a 3-amino group and a 2-cyano-phenyl group. The molecule is further protected by a fluorenylmethyloxycarbonyl (Fmoc) group, which is crucial for its role in synthesis processes. Fmoc-(R)-3-Amino-4-(2-cyano-phenyl)-butyric acid is recognized for its capacity to introduce a range of functionality and biological activity into peptides, thereby establishing its significance in drug discovery, biochemical research, and the advancement of peptide-based therapeutics.

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  • (R)-3-((((9H-FLUOREN-9-YL)METHOXY)CARBONYL)AMINO)-4-(2-CYANOPHENYL)BUTANOIC ACID

    Cas No: 269726-81-0

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  • 269726-81-0 Structure
  • Basic information

    1. Product Name: FMOC-(R)-3-AMINO-4-(2-CYANO-PHENYL)-BUTYRIC ACID
    2. Synonyms: N-(9-FLUORENYLMETHOXYCARBONYL)-(R)-3-AMINO-4-(2-CYANOPHENYL)BUTANOIC ACID;N-BETA-(9-FLUORENYLMETHOXYCARBONYL)-D-HOMO(2-CYANOPHENYL)ALANINE;RARECHEM AK PT F022;FMOC-2-CYANO-D-BETA-HOMOPHENYLALANINE;FMOC-D-PHE(2-CN)-(C*CH2)OH;FMOC-D-BETA-HOPHE(2-CN)-OH;FMOC-(R)-3-AMINO-4-(2-CYANOPHENYL)BUTANOIC ACID;FMOC-(R)-3-AMINO-4-(2-CYANO-PHENYL)-BUTYRIC ACID
    3. CAS NO:269726-81-0
    4. Molecular Formula: C26H22N2O4
    5. Molecular Weight: 426.46
    6. EINECS: N/A
    7. Product Categories: 3-Amino-4-phenylbutanoic Acid Analogs;B-Amino
    8. Mol File: 269726-81-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 678 °C at 760 mmHg
    3. Flash Point: 363.8 °C
    4. Appearance: /
    5. Density: 1.33 g/cm3
    6. Vapor Pressure: 2.61E-19mmHg at 25°C
    7. Refractive Index: 1.662
    8. Storage Temp.: 2-8°C
    9. Solubility: N/A
    10. CAS DataBase Reference: FMOC-(R)-3-AMINO-4-(2-CYANO-PHENYL)-BUTYRIC ACID(CAS DataBase Reference)
    11. NIST Chemistry Reference: FMOC-(R)-3-AMINO-4-(2-CYANO-PHENYL)-BUTYRIC ACID(269726-81-0)
    12. EPA Substance Registry System: FMOC-(R)-3-AMINO-4-(2-CYANO-PHENYL)-BUTYRIC ACID(269726-81-0)
  • Safety Data

    1. Hazard Codes: T
    2. Statements: 25
    3. Safety Statements: 45
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 269726-81-0(Hazardous Substances Data)

269726-81-0 Usage

Uses

Used in Pharmaceutical and Biochemical Research:
Fmoc-(R)-3-Amino-4-(2-cyano-phenyl)-butyric acid serves as a critical building block in solid-phase peptide synthesis. It is instrumental in the incorporation of the (R)-3-Amino-4-(2-cyano-phenyl)-butyric acid residue into growing peptide chains. This incorporation is vital for the development of peptides with specific biological activities, which can be explored for potential therapeutic applications.
Used in Drug Discovery:
In the realm of drug discovery, Fmoc-(R)-3-Amino-4-(2-cyano-phenyl)-butyric acid is used to create novel peptide-based drugs. Its unique structural features allow for the design of peptides with enhanced biological functions, which can be optimized for targeting various medical conditions.
Used in Peptide-based Therapeutics Development:
Fmoc-(R)-3-Amino-4-(2-cyano-phenyl)-butyric acid is also utilized in the development of peptide-based therapeutics. Its ability to introduce diverse functionality into peptides makes it a valuable asset in the creation of new treatments that can address unmet medical needs.

Check Digit Verification of cas no

The CAS Registry Mumber 269726-81-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,9,7,2 and 6 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 269726-81:
(8*2)+(7*6)+(6*9)+(5*7)+(4*2)+(3*6)+(2*8)+(1*1)=190
190 % 10 = 0
So 269726-81-0 is a valid CAS Registry Number.
InChI:InChI=1/C26H22N2O4/c27-15-18-8-2-1-7-17(18)13-19(14-25(29)30)28-26(31)32-16-24-22-11-5-3-9-20(22)21-10-4-6-12-23(21)24/h1-12,19,24H,13-14,16H2,(H,28,31)(H,29,30)/t19-/m1/s1

269726-81-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name Fmoc-(R)-3-amino-4-(2-cyanophenyl)-butyric acid

1.2 Other means of identification

Product number -
Other names RARECHEM AK PT F022

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:269726-81-0 SDS

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