269727-10-8

Usage

Uses

Used in Organic Synthesis:
(HO)2⁽¹⁰⁾BC₆H₄CHO is used as a reagent in the field of organic synthesis for its strong reducing properties, which can facilitate various chemical reactions and help in the formation of new compounds.
Used in Reducing Agent Applications:
In the chemical industry, (HO)2⁽¹⁰⁾BC₆H₄CHO is utilized as a reducing agent due to its ability to donate electrons to other substances, thus facilitating important chemical transformations.
Used in High-Energy Fuels Production:
(HO)2⁽¹⁰⁾BC₆H₄CHO is also considered for use in the production of high-energy fuels, capitalizing on its high reactivity and energy content.
Used in Research and Development:
Due to its unique structure and properties, (HO)2⁽¹⁰⁾BC₆H₄CHO is employed in research and development for exploring new chemical reactions, understanding its reactivity, and potentially discovering new applications in various fields.

Upstream product

• 61568-53-4 2-(ortho-bromophenyl)-1,3-dioxane 

Downstream Products

• 269727-14-2 (HO)2⁽¹⁰⁾BC₆H₄CH⁽¹⁵⁾NOC₆H₄CH₂N(CH₃)CH₂C₆H₃(ONCHC₆H₄⁽¹⁰⁾B(OH)2)2 

Relevant academic research and scientific papers

Conjugation of phenylboronic acid moiety through multistep organic transformations on nanodiamond surface for an anticancer nanodrug for boron neutron capture therapy

Detonation nanodiamonds (DNDs) have attracted considerable attention, in particular, in the field of nanomedicine due to their biocompatibility as well as various functionalities imparted by surface modification. Meanwhile, boron neutron capture therapy (BNCT) is an advanced cancer treatment utilizing nuclear fission reaction of 10B upon neutron irradiation. Recently, quite a few boron-containing nanoparticles have been investigated to deliver 10B atoms into cancer tissue selectively and retentively. In this study, we explored boronic acid functionalized DNDs as an anticancer agent for BNCT. Phenylboronic acid (PBA) moiety was introduced to poly-glycerol (PG) modified DNDs (DND-PG) through multistep organic transformation, giving percent order of boron atoms. The process is scalable and reliable by simple covalent chemistry and the resulting product is well dispersed, and stable chemically and physically under physiological conditions. In the in vivo experiments, the resulting material was accumulated in the tumor to exert BNCT efficacy upon neutron irradiation. These results demonstrate that the PBA functionalized DNDs are a promising candidate as an anticancer nanodrug for BNCT.

Regiochemical tagging: A new tool for structural characterization of isomeric components in combinatorial mixtures

In this contribution we present a new combined synthetic and analytical strategy (regiochemical tagging) that allows facile determination of complete structure, including substituent position and regiochemistry, of mass- redundant components in complex co