26974-79-8

Upstream product

• 88-74-4 2-nitro-aniline 
• 15486-96-1 3-Bromopropionyl chloride 
• 927-58-2 4-bromobutyroyl chloride 

Downstream Products

• 100239-40-5 3-(1,3,4,6,11,11a-Hexahydro-pyrazino[1,2-b]isoquinolin-2-yl)-N-(2-nitro-phenyl)-propionamide 
• 100222-03-5 3-(3,4,6,7,12,12a-Hexahydro-1H-pyrazino[1',2':1,6]pyrido[3,4-b]indol-2-yl)-N-(2-nitro-phenyl)-propionamide 
• 100222-07-9 3-(4-Benzyl-piperazin-1-yl)-N-(2-nitro-phenyl)-propionamide 

Relevant academic research and scientific papers

Synthesis, biological evaluation, and quantitative structure. A new class of potent H1 antagonists

Some [β-(Aroylamino)ethyl]piperazines and -piperidines and [2-[(Arylamino)carbonyl]ethyl]piperazines, -piperidines, -pyrazinopyridoindoles, and -pyrazinoisoquinolines have been synthesized and their H1-antagonistic activity studied in isolated guinea pig

NOVEL FERROPORTIN INHIBITORS

The invention relates to novel ferroportin inhibitors of the general formula (I) pharmaceutical compositions comprising them and the use thereof as medicaments, in particular for the prophylaxis and/or treatment of diseases caused by a lack of hepcidin or iron metabolism disorders, such as particularly iron overload states such as in particular thalassemia and hemochromatosis.