269740-17-2Relevant academic research and scientific papers
Syntheses and structure-activity relationships of novel 3′-difluoromethyl and 3′-trifluoromethyl-taxoids
Kuznetsova, Larissa V.,Pepe, Antonella,Ungureanu, Ioana M.,Pera, Paula,Bernacki, Ralph J.,Ojima, Iwao
scheme or table, p. 817 - 828 (2009/04/06)
A series of novel 3′-difluoromethyl-taxoids and 3′-trifluoromethyl-taxoids with modifications at the C2 and C10 positions were synthesized and evaluated for their in vitro cytotoxicities against human breast carcinoma (MCF7-S, MCF7-R, LCC6-WT, LCC6-MDR),
