26977-46-8

Basic information

• Product Name: N-(p-tolyl)-1H-indole-3-carboxamide
• Synonyms: N-(p-tolyl)-1H-indole-3-carboxamide
• CAS NO: 26977-46-8
• Molecular Weight: 250.3
• Mol File: 26977-46-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(p-tolyl)-1H-indole-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(p-tolyl)-1H-indole-3-carboxamide(26977-46-8)
• EPA Substance Registry System: N-(p-tolyl)-1H-indole-3-carboxamide(26977-46-8)

Safety Data

• Hazardous Substances Data: 26977-46-8(Hazardous Substances Data)

Upstream product

• 5457-28-3 3-cyano-1H-indole 
• 1204518-02-4 4-methylphenyl(2,4,6-trimethylphenyl)iodonium triflate 
• 22980-09-2 indolyl-3-glyoxylyl chloride 
• 59496-25-2 Indole-3-carbonyl chloride 
• 771-50-6 1H-indole-3-carboxylic acid 
• 106-49-0 p-toluidine 
• 225782-33-2 Indol-3-ylcarbonyl isothiocyanate 

Relevant articles and documents

Chemoselective Cu-catalyzed synthesis of diverseN-arylindole carboxamides, β-oxo amides andN-arylindole-3-carbonitriles using diaryliodonium salts

Chemoselective copper-catalyzed synthesis of diverseN-arylindole-3-carboxamides, β-oxo amides andN-arylindole-3-carbonitriles from readily accessible indole-3-carbonitriles, α-cyano ketones and diaryliodonium salts has been developed. DiverseN-arylindole-3-carboxamides and β-oxo amides were successfully achieved in high yields under copper-catalyzed neutral reaction conditions, and the addition of an organic base (DIPEA) resulted in a completely different selectivity pattern to produceN-arylindole-3-carbonitriles. Moreover, the importance of the developed methodology was realized by the synthesis of indoloquinolones andN-((1H-indol-3-yl)methyl)aniline and by a single-step gram-scale synthesis of the naturally occurring cephalandole A analogue.