2698-14-8

Basic information

• Product Name: 1-(1-Propenyl)-4-methylbenzene
• Synonyms: 1-(1-Propenyl)-4-methylbenzene;1-Methyl-4-(1-propenyl)benzene;4,β-Dimethylstyrene
• CAS NO: 2698-14-8
• Molecular Formula: C₁₀H₁₂
• Molecular Weight: 132.2
• Mol File: 2698-14-8.mol
• Article Data: 14

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(1-Propenyl)-4-methylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-Propenyl)-4-methylbenzene(2698-14-8)
• EPA Substance Registry System: 1-(1-Propenyl)-4-methylbenzene(2698-14-8)

Safety Data

• Hazardous Substances Data: 2698-14-8(Hazardous Substances Data)

Usage

General Description

1-(1-Propenyl)-4-methylbenzene, also known as isoeugenol, is a chemical compound commonly found in essential oils of various plants such as ylang-ylang, nutmeg, and basil. It is a colorless to pale yellow liquid with a pungent, spicy, and floral odor. Isoeugenol is used in the fragrance and flavor industry as a component in perfumes, soaps, and food flavorings. It also has potential pharmaceutical applications for its antimicrobial and anti-inflammatory properties. However, isoeugenol is also known to cause skin irritation and is classified as a skin sensitizer, which can elicit allergic reactions in some individuals. Therefore, it is important to use caution and proper safety measures when handling and using products containing isoeugenol.

Upstream product

• 3333-13-9 p-allyltoluene 
• 25574-04-3 1-p-tolyl-1-propanol 
• 124-38-9 carbon dioxide 
• 104-85-8 para-methylbenzonitrile 
• 1530-32-1 ethyltriphenylphosphonium bromide 
• 104-87-0 4-methyl-benzaldehyde 
• 3066-75-9 allyl diethyl phosphate 
• 106-38-7 para-bromotoluene 
• 591-87-7 Allyl acetate 
• 106-95-6 allyl bromide 
• 928-55-2 ethyl 1-propenyl ether 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 108-88-3 toluene 
• 5337-93-9 4'-methylpropiophenone 

Downstream Products

• 1074-55-1 p-n-propyltoluene 
• 1616633-37-4 methyl (S)-2-(4-bromophenyl)-3-(4-propylphenyl)propanoate 
• 868748-02-1 3-methyl-4-(p-tolyl)butanal 
• 343271-83-0 1-(1,2-dibromo-propyl)-4-methyl-benzene 
• 77134-00-0 3-(4-methylphenyl)prop-2-enyl acetate 
• 99-94-5 p-Toluic acid 
• 64-11-9 4-methylamphetamine 
• 1504-75-2 3-(4-methylphenyl)acrylaldehyde 

Relevant articles and documents

Bifunctional Metal-Organic Layers for Tandem Catalytic Transformations Using Molecular Oxygen and Carbon Dioxide

Tandem catalytic reactions improve atom- and step-economy over traditional synthesis but are limited by the incompatibility of the required catalysts. Herein, we report the design of bifunctional metal-organic layers (MOLs), HfOTf-Fe and HfOTf-Mn, consisting of triflate (OTf)-capped Hf6 secondary building units (SBUs) as strong Lewis acidic centers and metalated TPY ligands as metal active sites for tandem catalytic transformations using O2 and CO2 as coreactants. HfOTf-Fe effectively transforms hydrocarbons into cyanohydrins via tandem oxidation with O2 and silylcyanation whereas HfOTf-Mn converts styrenes into styrene carbonates via tandem epoxidation and CO2 insertion. Density functional theory calculations revealed the involvement of a high-spin FeIV (S = 2) center in the challenging oxidation of the sp3 C-H bond. This work highlights the potential of MOLs as a tunable platform to incorporate multiple catalysts for tandem transformations.

Visible photocatalysis of novel oxime phosphonates: Synthesis of β-aminophosphonates

A novel type of oxime phosphonate was synthesized and used in the intermolecular cascade radical addition reaction of alkenes to access β-aminophosphonates via visible-light-driven N-centered iminyl radical-mediated and redox-neutral selective C-P single-bond cleavage in an active phosphorus radical route. The procedure is characterized by its ability to achieve the construction of Csp3-P and Csp3-N bonds without the requirement for oxidants and bases.

Alkene functionalization for the stereospecific synthesis of substituted aziridines by visible-light photoredox catalysis

A novel strategy involving visible-light-induced functionalization of alkenes for the synthesis of substituted aziridines was developed. The readily prepared N-protected 1-aminopyridinium salts were used for the generation of N-centered radicals. This approach allowed the synthesis of aziridines bearing various functional groups with excellent diastereoselectivity under mild conditions. Moreover, this protocol was successfully applied to prepare structurally diverse nitrogen-containing frameworks.