26982-20-7 Usage
Uses
Different sources of media describe the Uses of 26982-20-7 differently. You can refer to the following data:
1. Poly-L-arginine hydrochloride has been used:as polyelectrolyte solution in the synthesis of biodegradable capsulesas layer constituent, in the preparation of layer by layer (LbL) assembly of multilayer biodegradable shellsin assay for the determination of binding activity of C-reactive protein for polycationic ligands
2. Poly-L-arginine hydrochloride has been used:to generate complex with stimulatory RNA isRNA9.2 as in neutrophilsused in ribosomal RNA transfection into human monocytic THP-1 cellsfor coating alginate capsule beads
General Description
Poly-L-arginine hydrochloride (PLA) is a homopolyamino acid. PLA enhances membrane permeability compared to poly-L-lysine. It has applications as drug carrier, neuroprotective agent and in anticancer vaccines preparations. Peptide vaccines in conjugation with PLA promotes antigen-presenting cells (APCs) to generate T cell and elicit immunostimulant functionality.
Biochem/physiol Actions
Poly-L-arginine (PLA) possesses anti-bacterial activity. It has a greater capacity to enhance membrane permeability. PLA at lower concentration enhances cell proliferation and at higher concentration acts as antiproliferative agent.
Check Digit Verification of cas no
The CAS Registry Mumber 26982-20-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,6,9,8 and 2 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 26982-20:
(7*2)+(6*6)+(5*9)+(4*8)+(3*2)+(2*2)+(1*0)=137
137 % 10 = 7
So 26982-20-7 is a valid CAS Registry Number.
InChI:InChI=1/C18H38N12O4/c19-10(4-1-7-26-16(20)21)13(31)29-11(5-2-8-27-17(22)23)14(32)30-12(15(33)34)6-3-9-28-18(24)25/h10-12H,1-9,19H2,(H,29,31)(H,30,32)(H,33,34)(H4,20,21,26)(H4,22,23,27)(H4,24,25,28)/t10-,11-,12-/m0/s1