26995-94-8

Basic information

• Product Name: 3-(Methylthio)acrylic acid
• Synonyms: 3-(Methylthio)acrylic acid;3-(Methylthio)propenoic acid
• CAS NO: 26995-94-8
• Molecular Formula: C4H6O2S
• Molecular Weight: 118.15
• Mol File: 26995-94-8.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(Methylthio)acrylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(Methylthio)acrylic acid(26995-94-8)
• EPA Substance Registry System: 3-(Methylthio)acrylic acid(26995-94-8)

Safety Data

• Hazardous Substances Data: 26995-94-8(Hazardous Substances Data)

Upstream product

• 70424-09-8 (Z)-β-methylthiopropenoic acid 
• 74-93-1 methylthiol 
• 471-25-0 Propiolic acid 
• 5188-07-8 sodium thiomethoxide 
• 70238-51-6 S-petasin 
• 131424-34-5 3c-thiocyanato-acrylic acid 
• 74-88-4 methyl iodide 

Downstream Products

• 63068-43-9 (E)-3-Methanesulfonyl-acrylic acid 

Relevant articles and documents

SESQUITERPENOIDS FROM PETASITES FRAGRANS

Chemical analysis of Petasites fragrans yielded the eremophilane type of sesquiterpenes: petasol, isopetasol, S-petasin, neo-S-petasin, and a mixture of petasol derivatives, with caffeic acid methyl ester and a mixture of phytosterols.Their structures were elucidated by chemical and spectroscopic methods.Key Word Index - Petasites fragrans; Compositae; Senecioneae; eremophilane; petasol; isopetasol; S-petasin; neo-S-petasin.

Isolation of 2-Alkyl-4-quinolones with Unusual Side Chains from a Chinese Pseudomonas aeruginosa Isolate

Chemical investigation of a Pseudomonas aeruginosa strain isolated from Hebei, China, led to the isolation of a suite of quinolones, quinolone-N-oxides, and phenazines, the structures of which were elucidated by detailed spectroscopic analysis. Most notable among the secondary metabolites isolated was an unprecedented 4-quinolone containing an S-methyl group in the side chain and a new derivative including a phenyl ring in the side chain, which expand significantly the variety of structural motifs found in the quinolones and raise interesting questions about their biosynthesis.

Total synthesis and biological evaluation of methylgerambullone

First total synthesis of methylgerambullone (MGB, 1) isolated from Glycosmis angustifolia was completed via a convergent route. The effect of MGB on the contractile responses of the isolated guinea-pig ileum induced by acetylcholine was investigated. As a result, it showed a potent relaxation rate (78.66 ± 4.30% at 100 mg/L) in a concentration-dependent manner on longitudinal smooth muscle contraction of isolated guinea-pig ileum induced by 1 μM acetylcholine.