270064-69-2

Basic information

• Product Name: methyl 1-o-azidobenzyl-3-ethyl-2-oxo-cyclopentanecarboxylate
• Synonyms: methyl 1-o-azidobenzyl-3-ethyl-2-oxo-cyclopentanecarboxylate
• CAS NO: 270064-69-2
• Molecular Weight: 301.345
• Mol File: 270064-69-2.mol

Chemical Properties

• CAS DataBase Reference: methyl 1-o-azidobenzyl-3-ethyl-2-oxo-cyclopentanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 1-o-azidobenzyl-3-ethyl-2-oxo-cyclopentanecarboxylate(270064-69-2)
• EPA Substance Registry System: methyl 1-o-azidobenzyl-3-ethyl-2-oxo-cyclopentanecarboxylate(270064-69-2)

Safety Data

• Hazardous Substances Data: 270064-69-2(Hazardous Substances Data)

Upstream product

• 60887-96-9 methyl 3-ethyl-2-oxocyclopentanecarboxylate 
• 31553-17-0 1-azido-2-(bromomethyl)benzene 

Downstream Products

• 270064-76-1 {2-[8-(2-chloro-acetylamino)-5-ethyl-5-formyl-2-oxo-octyl]-phenyl}-carbamic acid tert-butyl ester 
• 270064-71-6 5-o-azidobenzyl-3-[2-cyanoethyl]-3-ethyl-cyclopentanone 
• 270064-70-5 1-(2-azido-benzyl)-3-(2-cyano-ethyl)-3-ethyl-2-oxo-cyclopentanecarboxylic acid methyl ester 

Relevant articles and documents

Total synthesis of (±)-aspidospermidine

(±)-Aspidospermidine (1) has been synthesized from readily available methyl 3-ethyl-2-oxocylopentanecarboxylate (17) in 5.9% yield over 13 steps. The key step of the synthesis is an intramolecular cascade reaction that simultaneously forms the B, C, and D rings of 1. A high-yielding method of closing the remaining E ring is also described.