270065-77-5 Usage
Uses
Used in Pharmaceutical Research:
BOC-(S)-3-AMINO-4-(3-TRIFLUOROMETHYL-PHENYL)-BUTYRIC ACID is used as a key intermediate in the synthesis of various pharmaceutical compounds for [application reason]. Its unique structural features, including the BOC protecting group and the trifluoromethyl-phenyl moiety, make it a valuable building block in the development of new drugs with improved pharmacological properties.
Used in Organic Synthesis:
In the field of organic synthesis, BOC-(S)-3-AMINO-4-(3-TRIFLUOROMETHYL-PHENYL)-BUTYRIC ACID is used as a versatile starting material for the preparation of a wide range of organic compounds. Its reactivity and functional groups allow for various chemical transformations, enabling the synthesis of complex molecules with potential applications in different industries.
Used in Drug Development:
BOC-(S)-3-AMINO-4-(3-TRIFLUOROMETHYL-PHENYL)-BUTYRIC ACID is used as a potential drug candidate in the development of new therapeutic agents. Its unique chemical structure and pharmacological properties make it a promising candidate for the treatment of various diseases and conditions. Further research and development are required to fully explore its potential and optimize its therapeutic efficacy.
Note: The specific application reasons and industries are not provided in the given materials. The above uses are based on the general information about the compound and its potential applications in pharmaceutical research, organic synthesis, and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 270065-77-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,7,0,0,6 and 5 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 270065-77:
(8*2)+(7*7)+(6*0)+(5*0)+(4*6)+(3*5)+(2*7)+(1*7)=125
125 % 10 = 5
So 270065-77-5 is a valid CAS Registry Number.
InChI:InChI=1/C16H20F3NO4/c1-15(2,3)24-14(23)20-12(9-13(21)22)8-10-5-4-6-11(7-10)16(17,18)19/h4-7,12H,8-9H2,1-3H3,(H,20,23)(H,21,22)/t12-/m0/s1
270065-77-5Relevant academic research and scientific papers
Discovery of potent and selective β-homophenylalanine based dipeptidyl peptidase IV inhibitors
Xu, Jinyou,Ok, Hyun O.,Gonzalez, Edward J.,Colwell Jr., Lawrence F.,Habulihaz, Bahanu,He, Huaibing,Leiting, Barbara,Lyons, Kathryn A.,Marsilio, Frank,Patel, Reshma A.,Wu, Joseph K.,Thornberry, Nancy A.,Weber, Ann E.,Parmee, Emma R.
, p. 4759 - 4762 (2007/10/03)
Modification of in-house screening lead β-aminoacyl proline 8 gave an equipotent thiazolidide 9. Extensive SAR studies on the phenyl ring of 9 led to the discovery of a novel series of potent and selective DP-IV inhibitors. Introduction of a fluorine at the 2-position proved to be crucial for the potency of this series. The 2,5-difluoro (22q) and 2,4,5-trifluoro (22t) analogues were potent inhibitors of DP-IV (IC50 = 270, 119 nM, respectively).
