27019-10-9

Basic information

• Product Name: 2-Benzyltetralin-1-ol
• Synonyms: 2-Benzyl-1,2,3,4-tetrahydro-1-naphthol;2-Benzyl-1,2,3,4-tetrahydronaphthalene-1-ol;2-Benzyltetralin-1-ol
• CAS NO: 27019-10-9
• Molecular Formula: C₁₇H₁₈O
• Molecular Weight: 238.32
• Mol File: 27019-10-9.mol
• Article Data: 21

Chemical Properties

• Melting Point: 113 °C
• Boiling Point: 397.8±11.0 °C(Predicted)
• Appearance: /
• Density: 1.126±0.06 g/cm3(Predicted)
• PKA: 14.33±0.40(Predicted)
• CAS DataBase Reference: 2-Benzyltetralin-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Benzyltetralin-1-ol(27019-10-9)
• EPA Substance Registry System: 2-Benzyltetralin-1-ol(27019-10-9)

Safety Data

• Hazardous Substances Data: 27019-10-9(Hazardous Substances Data)

Upstream product

• 6261-32-1 (E)-2-benzylidene-1-tetralone 
• 6261-31-0 2-benzylidene-1-tetralol 
• 132797-26-3 2-benzyl-1-tetralone 
• 100-52-7 benzaldehyde 
• 6261-32-1 2-benzylidene-1-tetralone 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 100-51-6 benzyl alcohol 
• 529-33-9 1,2,3,4-Tetrahydro-1-naphthol 
• 91-01-0 1,1-Diphenylmethanol 
• 253609-31-3 (1'R,1''R,2S,5''R)-2-[phenyl-1'-(2''-azabicyclo[3.3.0]octane-2''-yl)methyl]-1,2,3,4-tetrahydro-1-naphthalinone 
• 7007-34-3 1-(3,4-dihydro-1-naphthalenyl)pyrrolidine 
• 253609-34-6 (1R,1'R,1''R,2S,5''R)-2-[phenyl-1'-(2''-azabicyclo[3.3.0]octane-2''-yl)methyl]-1,2,3,4-tetrahydro-1-naphthalinol 
• 253609-35-7 (1S,1'R,1''R,2S,5''R)-2-[phenyl-1'-(2''-azabicyclo[3.3.0]octane-2''-yl)methyl]-1,2,3,4-tetrahydro-1-naphthalinol 

Downstream Products

• 129113-12-8 2Z-benzylidene-1,2,3,4-tetrahydronaphthalene 
• 129113-11-7 2-benzyl-1,4-dihydronaphthalene 
• 613-59-2 2-benzylnaphthalene 
• 157485-34-2 (S)-2-benzyl-1-tetralone 
• 78140-79-1 trans-2-benzyl-1,2,3,4-tetrahydronaphthalene-1-ol acetate 
• 27019-11-0 3-benzyl-1,2-dihydronaphthalene 

Relevant articles and documents

Asymmetric Hydrogenation of Racemic Allylic Alcohols via an Isomerization-Dynamic Kinetic Resolution Cascade

Prochiral racemic allylic alcohols are converted to enantioenriched chiral alcohols bearing adjacent stereocenters catalyzed by a diamine diphosphine Ru complex in the presence of tBuOK. The protocol features a broad substrate scope (56 examples) and high

Switchable β-alkylation of secondary alcohols with primary alcohols by a well-defined cobalt catalyst

β-alkylation of secondary alcohols with primary alcohols to selectively generate alcohols by a well-defined Co catalyst is presented. Remarkably, a low catalyst loading of 0.7 mol % can be employed for the reaction. More significantly, this study represents the first Co-catalyzed switchable alcohol/ketone synthesis by simply manipulating the reaction parameters. In addition, the transformation is environmentally friendly, with water as the only byproduct.

Iridium(I)-Catalyzed C-C and C-N Bond Formation Reactions via the Borrowing Hydrogen Strategy

Iridium(I) complexes having an imidazol-2-ylidene ligand with benzylic wingtips efficiently catalyzed the β-alkylation of secondary alcohols with primary alcohols and acceptorless dehydrogenative cyclization of 2-aminobenzyl alcohol with ketones through a borrowing hydrogen pathway. The β-alkylated alcohols, including cholesterol derivatives, and substituted quinolines were obtained in good yields by using a minute amount of the catalyst with a catalytic amount of NaOH or KOH under the air atmosphere, liberating water (and H2 in the case of quinoline synthesis) as the sole byproduct. Notably, this system demonstrated turnover numbers of 940 000 (for β-alkylation of secondary alcohols with primary alcohols by using down to 0.0001 mol % = 1 ppm of the catalyst) and 9200 (acceptorless dehydrogenative cyclization of 2-aminobenzyl alcohol with ketones).