27020-96-8 Usage
General Description
3-Trichloromethylbenzonitrile is a chemical compound with the formula C8H3Cl3N. It is a white to light yellow crystalline solid that is insoluble in water but soluble in organic solvents. 3-Trichloromethylbenzonitrile is used as an intermediate in the production of various pesticides, pharmaceuticals, and other organic compounds. It is also used as a precursor in the synthesis of dyes and pigments. However, it is important to handle this compound with care as it is toxic and may cause irritation to the skin, eyes, and respiratory system.
Check Digit Verification of cas no
The CAS Registry Mumber 27020-96-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,0,2 and 0 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 27020-96:
(7*2)+(6*7)+(5*0)+(4*2)+(3*0)+(2*9)+(1*6)=88
88 % 10 = 8
So 27020-96-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H4Cl3N/c9-8(10,11)7-3-1-2-6(4-7)5-12/h1-4H
27020-96-8Relevant articles and documents
Tele nucleophilic aromatic substitutions in 1-nitro-3- and 1,3-dinitro- 5-trichloromethylbenzene, and 3-trichloromethylbenzonitrile. A new synthesis of the 1,4-benzothiazine-3(4H)-one ring system from 3 nitrobenzoic acid
Giannopoulos, Thomas,Ferguson, John R.,Wakefield, Basil J.,Varvounis, George
, p. 447 - 453 (2007/10/03)
3-Trichloromethylnitrobenzene 2, 1,3-dinitro-5-trichloromethylbenzene 13 and 3-trichloromethylbenzonitrile 18 react with sodium methoxide to give 4- methoxy-3-nitrobenzaldehyde 6, 4-methoxy-3,5-dinitrobenzaldehyde 15 and 5- dimethoxymethyl-2-methoxybenzonitrile 19, respectively. Compounds 2 and 13 react with methyl thioglycolate to afford dichloromethylacetates 7 and 16, respectively. These products are the result of tele nucleophilic aromatic substitution. Compound 18 reacted with methyl thioglycolate to give acetate 20 resulting from nucleophilic displacement of cyanide. Reductive cyclisation of 7 afforded benzothiazine 11. (C) 2000 Elsevier Science Ltd.
