270248-07-2

Upstream product

• 1125-88-8 benzaldehyde dimethyl acetal 
• 270248-06-1 2-(trimethylsilyl) ethyl β-D-galactopyranosyl-(1-> 4)-6-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl-(1-> 3)-2,6-di-O-benzyl-β-D-galactopyranosyl-(1-> 4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside 

Relevant academic research and scientific papers

Synthetic sulfated glucuronosyl paragloboside (SGPG) and its use for the detection of autoimmune peripheral neuropathies

The sulfated glucuronosyl paragloboside SO4-3-GlcA(β1-3) Gal-(β1-4)GlcNAc(β1-3)Gal-(β1-4)Glcβ(1-1′)Cer (SGPG) is a specific constituent of the peripheral nervous system involved in human dysimmune neuropathies. Although it is highly immunogenic in human pathology, it is not a major constituent of peripheral nerve in humans. Pure SGPG is very difficult to obtain from natural sources, but is needed for the design of efficient and reproducible immunoassays. We describe a new chemical synthesis of this important glycolipid with a stearic tail, including its complete characterization by mass spectrometry and its use in the detection of autoimmune neuropathies.

Synthesis and NMR study of a heptasaccharide, epitope of the stage-specific embryonic antigen-1 (SSEA-1)

This paper describes an efficient synthesis of the β-2-trimethylsilylethyl glycoside of lacto-N-fucoheptaose based on a highly stereo- and regioselective glycosylation between a Lewis(x) trisaccharidic donor and a tetraol tetrasaccharidic acceptor. The ti