27049-60-1

Basic information

• Product Name: 4-methyl-N-[(E)-piperidin-1-ylmethylidene]benzenesulfonamide
• CAS NO: 27049-60-1
• Molecular Formula: C₁₃H₁₈N₂O₂S
• Molecular Weight: 266.3592
• Mol File: 27049-60-1.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 409.463°C at 760 mmHg
• Flash Point: 201.436°C
• Density: 1.212g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.588
• CAS DataBase Reference: 4-methyl-N-[(E)-piperidin-1-ylmethylidene]benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-N-[(E)-piperidin-1-ylmethylidene]benzenesulfonamide(27049-60-1)
• EPA Substance Registry System: 4-methyl-N-[(E)-piperidin-1-ylmethylidene]benzenesulfonamide(27049-60-1)

Safety Data

• Hazardous Substances Data: 27049-60-1(Hazardous Substances Data)

Upstream product

• 2591-86-8 N-Formylpiperidine 
• 4083-64-1 Tosyl isocyanate 
• 110-89-4 piperidine 
• 51608-61-8 N-(2,2,2-trichloroethyliden)-p-toluenesulfonamide 
• 941-55-9 4-toluenesulfonyl azide 
• 92050-43-6 methyl β-piperidinomethacrylate 
• 5211-86-9 N-(dimethoxymethyl)piperidine 
• 70-55-3 toluene-4-sulfonamide 
• 766-09-6 1-ethyl-piperidine 
• 21849-40-1 dibromamine-T 
• 3695-00-9 di(4-tosyl)amine 
• 98-59-9 p-toluenesulfonyl chloride 
• 626-67-5 N-methylcyclohexylamine 
• 830-43-3 4-(trifluoromethyl)benzenesulfonamide 

Relevant articles and documents

Visible-light enabled room-temperature dealkylative imidation of secondary and tertiary amines promoted by aerobic ruthenium catalysis

Employing sulfonyl azide as a nitrogen donor, a visible-light-enabled aerobic dealkylative imidation of tertiary and secondary amines involving C(sp3)-C(sp3) bond cleavage with moderate to excellent yields at room temperature is described. It has been demonstrated that this imidation could take place spontaneously upon visible-light irradiation, and could be facilitated considerably by a ruthenium photocatalyst and oxygen. An alternative mechanism to the previous aerobic photoredox pathway has also been proposed.

Electrochemically generatedN-iodoaminium species as key intermediates for selective methyl sulphonylimination of tertiary amines

Reported herein is a straightforward protocol for approachingN-sulphonylamidinesviaan electricity-driven, iodine-mediated cross dehydrogenative condensation (CDC) between sulphonamides and tertiary amines, which features exclusive N-CH3selectivity for the amine partners. Mechanistic studies indicate that anin situgeneratedN-iodoaminium species serves as the key intermediate.

Visible-Light-Mediated Sulfonylimination of Tertiary Amines with Sulfonylazides Involving Csp3-Csp3 Bond Cleavage

Visible-light-induced cross-coupling of arylsulfonyl azides with tertiaryamines in the presence of Eosin Y at room temperature has been achieved. This transformation features alkyl C-C bond cleavage and provides a green approach to N-sulfonylamidines under mild conditions.