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(2-AMINO-THIAZOL-5-YL)-(4-CHLORO-PHENYL)-METHANONE is a chemical compound that features a thiazole ring with an amino group, a phenyl ring with a chlorine substituent, and a methanone functional group. It is widely utilized in pharmaceutical research and development for the synthesis of potential drug candidates due to its versatile structure and the broad range of biological activities exhibited by thiazole derivatives, such as antimicrobial, antiviral, antitumor, and anti-inflammatory properties.
Used in Pharmaceutical Industry:
(2-AMINO-THIAZOL-5-YL)-(4-CHLORO-PHENYL)-METHANONE is used as a key intermediate in the synthesis of drug molecules for its potential therapeutic applications. The presence of an amino group and a methanone functional group allows for the development of various drug candidates with different biological activities, making it a valuable building block in medicinal chemistry.
Used in Antimicrobial Applications:
In the field of antimicrobial research, (2-AMINO-THIAZOL-5-YL)-(4-CHLORO-PHENYL)-METHANONE is used as a starting material for the development of new antimicrobial agents. Its structure allows for the design of compounds that can target and inhibit essential microbial processes, contributing to the fight against drug-resistant infections.
Used in Antiviral Applications:
(2-AMINO-THIAZOL-5-YL)-(4-CHLORO-PHENYL)-METHANONE is also used in antiviral drug development, where its unique structure can be leveraged to create compounds that interfere with viral replication and infection processes, offering potential treatments for various viral diseases.
Used in Antitumor Applications:
In oncology, (2-AMINO-THIAZOL-5-YL)-(4-CHLORO-PHENYL)-METHANONE serves as a precursor for the synthesis of antitumor agents. Its ability to be modified and incorporated into various molecular frameworks makes it a promising candidate for the development of drugs targeting cancer cells.
Used in Anti-inflammatory Applications:
For anti-inflammatory drug development, (2-AMINO-THIAZOL-5-YL)-(4-CHLORO-PHENYL)-METHANONE is utilized as a component in the creation of compounds that can modulate inflammatory responses. Its presence in these molecules can help in the management of various inflammatory conditions by targeting specific pathways involved in inflammation.

27053-24-3

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27053-24-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 27053-24-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,0,5 and 3 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 27053-24:
(7*2)+(6*7)+(5*0)+(4*5)+(3*3)+(2*2)+(1*4)=93
93 % 10 = 3
So 27053-24-3 is a valid CAS Registry Number.

27053-24-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (2-amino-1,3-thiazol-5-yl)-(4-chlorophenyl)methanone

1.2 Other means of identification

Product number -
Other names 2-Amino-5-(p-chlorbenzoyl)thiazol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:27053-24-3 SDS

27053-24-3Downstream Products

27053-24-3Relevant academic research and scientific papers

Synthesis of 2-Amino-5-acylthiazoles by a Tertiary Amine-Promoted One-Pot Three-Component Cascade Cyclization Using Elemental Sulfur as a Sulfur Source

Fu, Rong-Geng,Wang, Yong,Xia, Fei,Zhang, Hao-Lin,Sun, Yuan,Yang, Duo-Wen,Wang, Ye-Wei,Yin, Peng

, p. 12237 - 12245 (2019/10/11)

A novel one-pot three-component cascade cyclization strategy for the synthesis of 2-amino-5-acylthiazoles using enaminones, cyanamide, and elemental sulfur has been developed. The reported methods have demonstrated good tolerance of various functional gro

2-Amino-5-acyl thiazole derivative and synthesis method thereof

-

Paragraph 0050-0051; 0053; 0116, (2019/10/01)

The invention relates to a technology for synthesis of organic compounds and discloses a 2-amino-5-acyl thiazole derivative and a synthesis method thereof. The structure of the 2-amino-5-acyl thiazolederivative is shown in a formula (I), and R in the form

2-amino-4-dimethylamino-1-thia-3-azabutadienes as precursors of thiazoles

Landreau,Deniaud,Reliquet,Meslin

, p. 2651 - 2659 (2007/10/03)

The reaction of 2-amino-4-dimethylamino-1-thia-3-azabutadienes 1 with α-bromoketones gave rise to 2-aminothiazoles 2 together with 2-(N,N-dimethylaminomethylenamino)thiazoles 3. Competitive mechanisms are described. Furthermore, reaction of diene 1a with

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